Tomivosertib was highly effective at blocking eIF4E phosphorylation on serine 209 in AML cells.
Moreover, combination of Tomivosertib and Venetoclax resulted in synergistic anti-leukemic responses in AML cell lines.
Mass spectrometry studies identified novel putative MNK1/2 interactors, while in parallel studies we demonstrated that MNK2 - RAPTOR - mTOR complexes are not disrupted by Tomivosertib.
Overall, these
Oncotarget findings demonstrate that Tomivosertib exhibits potent anti-leukemic properties on AML cells and support the development of clinical translational efforts involving the use of this drug, alone or in combination with other therapies for the treatment of AML. These
Oncotarget findings demonstrate that Tomivosertib exhibits potent anti-leukemic properties on AML cells and support the development of clinical translational efforts involving the use of this drug
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CHIEF OF PHARMACY Services Dr. Richard Rooney, Hospitalist Dr. Natasha Nichols from the Department of Medicine Services, and Emergency Management Specialist Mike Lackey.
On Saturday, January 9, Jesse Brown Veterans Affairs Medical Center (JBVA) staff members, Chief of Pharmacy Services Dr. Richard Rooney, Hospitalist Dr. Natasha Nichols from the Department of Medicine Services, and Emergency Management Specialist Mike Lackey, joined the America’s Heroes Group radio show to discuss the COVID-19 vaccine.
Jesse Brown received the COVID-19 vaccine on the morning of December 22 and began administering the vaccine that afternoon. Since then, Jesse Brown has administered more than 1,400 doses to high-risk veterans who are patients at Jesse Brown, as well as Jesse Brown employees. The VA is following vaccine priority guidelines set by the CDC.
Patrick Gleason
Patrick Gleason, Voluntary Service Chief at Jesse Brown Veterans Affairs Medical Center (JBVAMC) joined the America’s Heroes Group radio show on Saturday, December 12 to discuss food insecurity and the importance and role of the greater community in serving veterans.
The mission of Voluntary Services at Jesse Brown VA Medical Center is to improve the lives of those who have served the nation. Voluntary Services brings together and coordinates many of the resources that are available and needed in helping improve the lives of veterans.
While COVID-19 has made the work of serving veterans challenging, Voluntary Services continues to find ways to meet the needs.