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Lyme disease linked to increased risk of mental disorders, suicidality

In a new study, U.S. and Danish researchers report that patients who received a hospital diagnosis of Lyme disease inpatient, outpatient, or at the ER had a 28 percent higher rate of mental disorders and were twice as likely to have attempted suicide post-infection, compared to individuals without the diagnosis.

Despite antibiotics, Lyme infection persisted in woman s brain

The presence of the corkscrew-shaped Borrelia burgdorferi spirochetes in the former Lyme disease patient’s brain and spinal cord were evidence of a persistent infection. The 69-year-old woman, who experienced progressively debilitating neurological symptoms throughout her illness, decided to donate her brain to Columbia University for the study of the disease as her condition worsened. While she had first experienced the classic symptoms of Lyme disease 15 years prior and was treated accordingly after her diagnosis, she experienced continual neurological decline including a severe movement disorder and personality changes, and eventually succumbed to Lewy body dementia. “These findings underscore how persistent these spirochetes can be in spite of multiple rounds of antibiotics targeting them.”

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