New clues on why more men than women develop severe disease
A new study from Washington University School of Medicine in St. Louis suggests that, among men, low testosterone levels in the blood are linked to more severe COVID-19. The study contradicts widespread assumptions that higher testosterone may explain why men, on average, develop more severe COVID-19 than women do. (Image: Sara Moser)
May 25, 2021 SHARE
Throughout the pandemic, doctors have seen evidence that men with COVID-19 fare worse, on average, than women with the infection. One theory is that hormonal differences between men and women may make men more susceptible to severe disease. And since men have much more testosterone than women, some scientists have speculated that high levels of testosterone may be to blame.
May 18, 2021
Patients with stable coronary artery disease who received “complete” revascularization in the ISCHEMIA trial appear to have derived more clinical benefit with the invasive strategy than medical therapy over follow-up, a finding at odds with what was observed for the overall trial. The implication, say investigators, is that revascularization might offer clinical advantages over conservative medical therapy if all anatomically relevant lesions are treated.
This analysis, which focused only on the patients who had complete revascularization defined anatomically, showed that the primary composite endpoint occurred in 11.9% of patients treated invasively as opposed to 15.4% of patients who were treated medically.
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in Afghanistan.
It’s supposedly over, and I wasn’t happy. I didn’t cry until later. I just was empty. And if anything, I felt almost angry. It seemed like the announcement was coming not as a result of a watershed moment. It’s cliche, but it was definitely not with a bang, but with a whimper. There wasn’t a moment of reckoning. .
I remember there was this colonel who had talked to us right when we got into country. And he said, “I want you to remember that not a single thing you do out here is worth the life of a single Marine.”
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The difficulty of learning the technology behind mRNA vaccines poses a major obstacle to President Joe Biden s proposal aiding poor countries by defying the pharmaceutical industry and waiving patent protections for COVID-19 vaccines.
The rationale for the patent waiver would be to allow developing countries to reproduce currently existing COVID-19 vaccines without having to worry about getting sued by the pharmaceutical companies that hold the patents.
But in the case of the mRNA vaccines produced by Pfizer/BioNTech and Moderna, doing so would be very difficult. As of March, mRNA vaccines accounted for 43% of the COVID-19 vaccines produced, according to British software company Airfinity.