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Discovery may enable the development of new therapies to kill aggressive cancer cells
The idea
Vanderbilt faculty and researchers are looking for the Achilles heel of the cancer cells that survive initial chemotherapy. Michael King, chair of the Department of Biomedical Engineering, and Joshua D. Greenlee, graduate research fellow in biomedical engineering, are investigating whether a naturally occurring protein made in immune cells, called TRAIL, is effective in killing colon cancer cells.
This knowledge may enable the development of new therapies that make aggressive cancer cells easier to kill off before they spread to other parts of the body.
The researchers found that TRAIL is more effective in killing these drug resistant colon cancer cells.