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Enzyme Blocks The Formation Of New Blood Vessels in Cancer

Enzyme Blocks The Formation Of New Blood Vessels in Cancer by Pooja Shete on  December 24, 2020 at 10:04 PM Almost all the living things require oxygen to grow including cancerous tumors. A feature of the tumors is that it can develop new blood vessels (angiogenesis) if they do not get enough oxygen in order to survive. The research conducted by Xiang-Lei Yang, PhD, a professor In the Department of Molecular Medicine at Scripps Research is published in the journal PLOS Biology. The study points to the exact molecular machinery that leads to angiogenesis providing scientific insights that can help develop drugs to kill tumors and stop their spread in the body.

Researchers uncover key regulation step that inhibits tumor growth

Researchers uncover key regulation step that inhibits tumor growth Most living things need oxygen to grow and thrive. Even cancerous tumors. That s why tumors will readily sprout new blood vessels if their oxygen is starved, creating new lifelines for survival. A study published today from Scripps Research pinpoints the precise molecular machinery that makes this happen, providing scientific insights that can potentially be translated into medicines that help kill tumors and stop cancer from spreading in the body. The findings also may enable new interventions that promote healthy blood-vessel development for people with heart disease and other conditions, says the study s leader Xiang-Lei Yang, PhD, a professor In the Department of Molecular Medicine at Scripps Research.

Enzyme discovery can help rein in blood vessels that fuel cancer

 E-Mail LA JOLLA, CA Most living things need oxygen to grow and thrive. Even cancerous tumors. That s why tumors will readily sprout new blood vessels if their oxygen is starved, creating new lifelines for survival. A study published today from Scripps Research pinpoints the precise molecular machinery that makes this happen, providing scientific insights that can potentially be translated into medicines that help kill tumors and stop cancer from spreading in the body. The findings also may enable new interventions that promote healthy blood-vessel development for people with heart disease and other conditions, says the study s leader Xiang-Lei Yang, PhD, a professor In the Department of Molecular Medicine at Scripps Research.

Scientists demonstrate a promising strategy for treating lymphomas

Scientists demonstrate a promising strategy for treating lymphomas Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes. The new approach uses natural cancer-targeting immune cells, known as natural killer cells, that have been modified to selectively target lymphoma. As described in their study, published in the journal Angewandte Chemie, the modified natural killer cells brought about a dramatic reduction of lymphoma in a mouse. We found a way to achieve selectivity in targeting lymphoma cells, which is an important departure from existing therapies, says co-senior author Peng Wu, PhD, an associate professor in the Department of Molecular Medicine at Scripps Research.

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