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Engineered Nanobodies Help Combat SARS-CoV-2 Virus
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Nanobodies for COVID-19 found
23 Jun 2021, 04:56 GMT+10
Washington [US], June 22 (ANI): Scientists at Ohio State University are pursuing a new strategy in the protracted fight against the SARS-CoV-2 virus by engineering nanobodies that can neutralise virus variants in two different ways.
An accelerated article preview of the study was published online in the journal Nature.
In lab studies, researchers identified two groups of molecules that were effective against virus variants. Using different mechanisms, nanobodies in each group bypassed mutations and disabled the virus s ability to bind to the receptor that lets it enter host cells.
Though vaccination is enabling the resumption of some pre-pandemic activities in parts of the world, SARS-CoV-2 is rapidly working its way around vaccines by mutating itself. In this study, the nanobodies neutralised three emerging variants: Alpha, Beta and Gamma.