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WEST LAFAYETTE, Ind. When muscle is damaged, resident stem cells mediate the repair of the injured tissue. At the same time, circulating immune cells race to the site to aid the repair.
The presence of these infiltrating immune cells at injury sites raises questions about their role in coordinating with muscle stem cells to build or regenerate muscle tissue.
Shihuan Kuang, a Purdue professor of animal sciences, has identified a previously unknown subset of muscle stem cells, which he has dubbed “immunomyoblasts,” that have both muscle stem cell and immune cell properties and may shed light on how those cells interact.