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Novel immunotherapy boosts long-term stroke recovery in mice

 E-Mail IMAGE: These images show how regulatory T cells (Treg cells) boost the ability of microglia cells to promote the regeneration of the brain s white matter (right), compared to a sample not. view more  Credit: Xiaoming Hu/University of Pittsburgh PITTSBURGH, May 19, 2021 - Specialized immune cells that accumulate in the brain in the days and weeks after a stroke promote neural functions in mice, pointing to a potential immunotherapy that may boost recovery after the acute injury is over, University of Pittsburgh School of Medicine neurologists found. The study, published today in the journal Immunity, demonstrated that a population of specialized immune cells, called regulatory T (Treg) cells, serve as tissue repair engineers to promote functional recovery after stroke. Boosting Treg cells using an antibody complex treatment, originally designed as a therapy after transplantation and for diabetes, improved behavioral and cognitive functions for weeks after a s

Why Are Strokes Becoming More Common in Younger Women?

Medically Reviewed Rochelle Swanson (left, and with her husband and children, right) had an obscure risk factor when she suffered a stroke at age 39. Methodist Health System; Pam Stout/PJS Images Rochelle Swanson, a nurse in Gretna, Nebraska, knew exactly what was happening early on Christmas morning in 2020. She had stopped by a storage unit to grab her husband’s gift before starting her shift in the stroke unit at the hospital where she works. She ended up arriving as a patient. “I dropped the box I was holding and thought it was because it was heavy. I didn t realize that it was because my arm was flaccid. Right after that, I felt gravity pull the left side of my face down and my speech was garbled and slurred,” says Swanson. Despite being young just 39 years old she knew immediately that she was having a stroke.

Novel Immunotherapy Boosts Long-Term Stroke Recovery in Mice

Novel Immunotherapy Boosts Long-Term Stroke Recovery in Mice
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Struggling to save Indians from afar

On Thursday, April 23, I received a text from my 85 year-old mother: “Nina, Baby is in the hospital with COVID. Her oxygen level is very low. Just pray for her.” As an Indian-American physician and a family member, I couldn’t “just pray.” I felt a responsibility to save Baby.

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