PLD3 gene contributes to risk of Alzheimer s disease eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
More than a third of COVID-19 survivors suffer neurological and psychiatric effects, study finds
By Stephanie Weaver
FULL INTERVIEW: Dr. Anthony Fauci on COVID-19 vaccine boosters and mutations
Dr. Anthony Fauci, the nation’s leading expert on infectious diseases, said he feels confident in current indications of the enduring efficacy of COVID-19 vaccines, but variants of the virus present a worrisome wild card when factoring into the calculation of whether booster shots will be needed down the road.
LOS ANGELES - Since the COVID-19 pandemic began, there has been growing concern that survivors might be at an increased risk of brain disorders. Now, a new study shows that more than one in three COVID-19 survivors may suffer from longer-term neurological and psychiatric effects from the virus.
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IMAGE: This image shows the close relationship between phospholipase D3 and the pathological hallmarks of Alzheimer s disease in tissue from the temporal lobe of a human brain. Phospholipase D3, which is. view more
Credit: Matthew Schrag
A rare and controversial mutation in the phospholipase D3 (PLD3) protein - previously linked to Alzheimer s disease - interferes with PLD3 s vital recycling function inside neurons. Matthew Schrag of Vanderbilt University Medical Center and colleagues report these new findings in a paper published April 8th in
PLOS Genetics.
About 1 percent of people with Alzheimer s disease carry a specific mutation in their PLD3 gene. The question of whether or not this mutation leads to Alzheimer s disease has remained controversial, however, due to its rarity and because the protein s function was previously unknown. In the new study, Schrag s team delved deeper into the function of this gene and its link to the disease. The researchers
Psychiatric and neurological problems are common after COVID latimes.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from latimes.com Daily Mail and Mail on Sunday newspapers.
Credit: Esther Max, Flickr. Rotated from original.
Women may be at greater risk of experiencing chronic pain because the condition has a different genetic basis in men and women. Keira Johnston of the University of Glasgow and colleagues report these findings in a new study published April 8th in
PLOS Genetics.
Chronic pain is a common and potentially debilitating condition that tends to affect more women than men. To explore this disparity, researchers undertook the largest ever genetic study of chronic pain that analyzed women and men separately. They looked for genetic variants associated with chronic pain in 209,093 women and 178,556 men, and compared the results. In women, 31 genes were associated with chronic pain, while 37 genes were linked in men. A single gene was associated with chronic pain in both sexes. The researchers also investigated whether the activity of these genes was turned up or down in tissues known to be related to chronic pain. They found that all 37 ge