MedCity News
This week, read new developments at Carrum Health, Seven Bridges, CARISMA Therapeutics, and more.
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Seven Bridges recently announced the formation of its strategic advisory board tasked with advising Seven Bridges leadership team in its mission to accelerate scientific discovery and speed the path from raw experimental data to new treatments and diagnostics. The appointment of three leaders with significant experience in healthcare and artificial intelligence will aid the company exploring new health-focused opportunities and bolster the company’s work with biopharmaceutical and academic researchers to significantly decrease the time, cost, and risk in the discovery-through-
commercialization cycle for novel precision medicines and therapies.
March 4, 2021 at 6:30 am
It’s been about 20 years since scientists unveiled a rough draft of the human genome. This is all of the DNA found in a human cell. Think of it like a genetic instruction book for the body. Creating that rough draft was like a medical moonshot. It held out the promise that doctors might soon be able look at someone’s DNA and prescribe the right medicines for their illness. They might even prevent certain diseases.
That promise is known as precision medicine. But it has yet to be fulfilled in any widespread way.
Researchers are getting clues about some DNA variants linked to certain conditions. Some people have them. Others might not. And scientists have figured out how some variants affect the way drugs work in the body. But many of those advances have helped just one group: people whose ancestors came from Europe. In other words, white people.
Genomic Medicine Stands on the Shoulders of Giants
Source: Boris SV/Getty Images
Genomic Medicine Stands on the Shoulders of Giants
With the benefit of rich, diverse data stores and computational power, scientists in precision medicine are finally realizing ambitions inspired long ago by the Human Genome Project
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When the first published drafts of the human genome appeared 20 years ago, scientists proclaimed that an outpouring of genomically informed medical advances was imminent. For example, Francis S. Collins, MD, PhD, then director of the National Human Genome Research Institute, and Victor A. McKusick, MD, professor of medical genetics at Johns Hopkins University, predicted that by 2020, the impact of genetics on medicine would be “widespread.” They shared more detailed expectations in a paper titled, “Implications of the Human Genome Project for Medical Science” (
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