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Existing drug may be effective in treating COVID-19 A new University of Chicago study has found that the drug masitinib may be effective in treating COVID-19. The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2 in human cell cultures and in a mouse model, leading to much lower viral loads. Researchers at UChicago s Pritzker School of Molecular Engineering (PME), working with collaborators at Argonne National Laboratory and around the world, also found that the drug could be effective against many types of coronaviruses and picornaviruses. Because of the way it inhibits replication, it has also been shown to remain effective in the face of COVID-19 variants.

Glenn randallSavas tayAndrzej jaochimaikEmily hendersonUchicago pritzker school of molecular engineeringUniversity of chicagoArgonne national laboratoryUniversity of louisvilleHoward taylor ricketts laboratoryPritzker schoolMolecular engineeringNir draymanArgonne nationalக்ளென் ரேண்டால்சவாஸ் தாய்எமிலி ஹென்டர்சன்