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James T Gorman, retired pharmaceutical salesman who was an advocate of Multiple System Atrophy awareness, dies

James T Gorman, retired pharmaceutical salesman who was an advocate of Multiple System Atrophy awareness, dies
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Global Roundup: EU Approves ViiV s HIV-1 Drug and More

Published: Dec 24, 2020 By Alex Keown The European Union (EU) authorized ViiV Healthcare’s Vocabria (cabotegravir injection and tablets) in conjunction with Janssen’s Edurant (rilpivirine tablets) for the treatment of HIV-1 infection in adults who are virologically suppressed. Vocabria is intended for adults who are virologically suppressed on a stable antiretroviral regimen without present or past evidence of viral resistance to, and no prior virological failure with agents of the NNRTI and INI class. The approval of ViiV’s treatment is the first time HIV-1 patients in Europe may be able to receive a long-acting injectable treatment that removes the need to take daily oral tablets, following the oral initiation phase.

IPO Alert: Inhibikase Therapeutics (IKT)

IPO Alert: Inhibikase Therapeutics (IKT) BRUSSELS/FRANKFURT/PARIS (dpa-AFX) - Inhibikase Therapeutics is scheduled to make its debut on the Nasdaq Global Select Market today (December 23), under the ticker symbol IKT. Atlanta, Georgia-based Inhibikase Therapeutics is a clinical stage pharmaceutical company developing therapeutics kinase inhibitors for Parkinson s disease and related disorders. The company has offered to sell 1.8 million shares of its common stock at a price of $10 each. The underwriters have an option for a period of 45 days to purchase up to an additional 270 thousand shares. The offering, which is scheduled to close on December 28, is expected to fetch gross proceeds of about $18 million for the company.

MODAG Initiates First-in-Patient Phase 1b Trial for Anle138b in Parkinson s Disease

MODAG Initiates First-in-Patient Phase 1b Trial for Anle138b in Parkinson s Disease MODAG, a German biotechnology company focused on the development of disease-modifying small molecule therapeutics for neurodegenerative diseases, today announced the clinical trial initiation of a first-in-patient Phase 1b study for anle138b in patients with mild to moderate Parkinson s Disease (PD). Anle138b is a disease-modifying treatment option for synucleinopathies, such as Multiple System Atrophy (MSA) and PD. The short-term Phase 1b study with PD patients will be conducted by Quotient Sciences in Nottingham, UK, supported by the Neurology Department of Nottingham University Hospital. The study s primary endpoints include safety, tolerability and pharmacokinetics of anle138b in PD patients in order to establish the optimal dosing scheme for future long-term efficacy trials. The trial is supported by a grant of USD 1.4 million from The Michael J. Fox Foundation for Parkinson s Research.

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