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IMAGE: These results suggest that the cyclin D2-cardiomyocyte transplantation may be a potential therapeutic strategy for the repair of infarcted hearts, said study leader Jianyi Jay Zhang, M.D., Ph.D., the chair. view more
Credit: UAB
BIRMINGHAM, Ala. - In a large-animal study, researchers have shown that heart attack recovery is aided by injection of heart muscle cells derived from human induced pluripotent stem cell line, or hiPSCs, that overexpress cyclin D2. This research, published in the journal
Circulation, used a pig model of heart attacks, which more closely resembles the human heart in size and physiology, and thus has higher clinical relevance to human disease, compared to studies in mice.
Children infected with COVID-19 may not show typical symptoms, experts say
TORONTO, Ontario (CTV Network) A new study has found that the majority of children infected with COVID-19 may not show typical symptoms including fever, cough or shortness of breath.
As a result, the study’s authors say more vigilance is needed when screening children for SARS-CoV-2, the virus that causes COVID-19.
The study, conducted by researchers out of the University of Alabama at Birmingham (UAB), also found that children with COVID-19 may develop poor clinical outcomes such as hospitalization and mechanical ventilation.
“While the rates of poor clinical outcomes are relatively lower in children when compared to adults, 5-6 per cent still required hospitalization. Among those hospitalized, 18 per cent required critical care and 4 per cent needed a ventilator for breathing,” Vibhu Parcha, a clinical research fellow at UAB and the study’s lead author, said in a press release.
49ers Sign 10 Rookies
14 May 2021, 23:44 GMT+10
The San Francisco 49ers announced on Thursday that they have signed five of the team s eight draft picks, each to four-year deals, along with five undrafted rookie free agents.
Draft Pick Signings Undrafted Signings Draft Pick Player Bios
Aaron Banks (6-5, 325) was selected by the 49ers in the second round (48th overall) of this year s NFL Draft out of Notre Dame. He appeared in 38 games (31 starts) in four years (2017-20) at Notre Dame. As a senior in 2020, he started all 12 games, including an appearance in the CFP Semifinal and was named First-Team AFCA All-America and Associated Press First-Team All-America. He started all 13 games as a junior in 2019 and helped the Irish rank 13th nationally in scoring offense after playing in all 13 games (six starts) as a sophomore in 2018. He did not see game action as a freshman in 2017.
Researchers looked at more than 12,300 children under age 18 who tested positive for COVID-19
Nearly 75% of infected children did not have symptoms such as cough, fever or shortness of breath
More than 5% of kids ended up hospitalized and they were up to five times more likely to experience coronavirus symptoms
Serious symptoms were up to three times more likely among infants, toddlers and pre-schoolers with COVID-19 compared to adolescents
Black and Hispanic children were more likely to be hospitalized with Covid, 6.5% and 4.6%, respectively, compared to white children at 3.3%
Genkyotex Provides Business Update and Reports Cash Position at March 31, 2021
Rights issue of €5 million in March 2021 completed
Positive data from Phase 1 clinical trial of high-dose setanaxib
Regulatory News:
Genkyotex (Euronext Paris Brussels: FR0013399474 GKTX) (Paris:GKTX) (Brussels:GKTX), a biopharmaceutical company and the leader in NOX therapies, today reported cash and cash equivalents of €3.8 million as of March 31, 2021. The existing cash and cash equivalents provide cash runway to end of July 2021.
Business update
On March 24, 2021, the Company announced that it had raised €5 million through a rights issue in France. Following this capital increase, the Company s main shareholder, Calliditas Therapeutics AB (publ), holds 90.2% of the share capital and voting rights of the Company.