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‘Shot in the Dark’ Provides a Path Toward Collaborative Research That Better Predicts COVID-19 Severity
February 3, 2021 GMT
Sanmi Koejo, assistant professor of computer science, University of Illinois Urbana-Champaign
URBANA, Ill. - February 3, 2021 - ( Newswire.com )
A chance phone call between a physician and an artificial intelligence expert at University of Illinois Urbana-Champaign has led to a neural network tool that can read X-rays and better predict potential health complications from COVID-19 and other causes.
Dr. Ayis Pyrros said his call three years ago to David Forsyth, a professor of computer science at UIUC’s Grainger College of Engineering, was a “shot in the dark.”
Retrained Generic Antibodies can Recognize SARS-CoV-2, Says Study by Colleen Fleiss on February 3, 2021 at 11:27 PM
A new strategy that redirects antibodies for other diseases existing in humans to the spike proteins of SARS-CoV-2 has been discovered by University of Illinois Chicago and California State University at Sacramento researchers.
Upon a vaccination or a real infection, it takes several weeks before the immunity develops antibodies that can selectively bind to these spike proteins. Such antibody-labeled viruses are neutralized by the natural killer and T cells operated by the human immunity.
An alternative approach to train the immunity response is offered by researchers at the University of Illinois Chicago and California State University at Sacramento who have developed a novel strategy that redirects antibodies for other diseases existing in humans to the spike proteins of SARS-CoV-2.
Doctor Kent Hoskins is an associate professor with UIC s division of hematology and oncology. We ve known for more than three decades that Black women in this country have at least a 40% higher mortality rate compared to other woman, said Hoskins. That s been generally attributed to inequities in high quality screening and high quality treatment, but we also know that the biology of the tumor plays a role.
A commonly-used test to decide who needs chemo therapy for breast cancer is not as accurate in Black woman because original studies that were done to develop that test had a very small representation of Black woman, less than 5%, according to Hoskins.
Feb 2, 2021
Black women have higher recurrence and higher mortality rates compared to non-Hispanic white women, for certain types of breast cancer, according to a University of Illinois Chicago researcher s study published recently in JAMA Oncology.
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IMAGE: Double-faced peptide-based boosters are computationally designed to allow recognition of SARS-CoV-2 (grey, schematic) by Hepatitis B antibodies. One booster face made of ACE2-mimic peptides (red) can bind to the receptor. view more
Credit: UIC
The SARS-CoV-2, the new coronavirus behind the current pandemic, infects humans by binding its surface-exposed spike proteins to ACE2 receptors exposed on the cell membranes.
Upon a vaccination or a real infection, it takes several weeks before the immunity develops antibodies that can selectively bind to these spike proteins. Such antibody-labeled viruses are neutralized by the natural killer and T cells operated by the human immunity.