CUHK unveils balance between two protein counteracting forces in hereditary ataxias eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
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Protein misfolding contributes to the pathogenesis of SCA3
Proteins play a significant role in every single cell development in the human body, including neurons. Numerous studies have proved that misfolds and aggregation of proteins contribute to many occurrences of human diseases. Proteins need to adopt proper folding and architecture before being able to execute their biological functions. Even a minor improper assembly of a protein may result in cellular malfunctioning, leading to toxic insoluble protein aggregates that cause diseases. Progressive misfolding of proteins and aggregates will interfere with the functionalities of other normal proteins, and these are also detected in the deteriorating neurons of SCA3 and other protein misfolding induced disorders, including polyglutamine (polyQ) diseases.
The social fibre of our communities has been pushed to the brink. Hopelessness is prevalent throughout our country. Despair is now commonplace. The challenges we now face were there before Covid-19, but the pandemic has certainly pronounced all our challenges tenfold. These are the difficult co.
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IMAGE: A screenshot from day one of the EINST4INE project kick off meeting held online view more
Credit: EINST4INE
EINST4INE (the European Training Network for InduStry Digital Transformation across Innovation Ecosystems) is a €4M research initiative addressing some of the gaps and challenges faced by industries adapting to the digital revolution.
In a virtual event on 8 and 10 February 2021, the consortium of European and Australian partners officially launched EINST4INE s 48-month programme.
With world-leading expertise in the areas of Open Innovation, Industry 4.0, digital transformation, and innovation ecosystems, the EINST4INE team will develop new methods, skills, concepts and roadmaps to guide businesses towards digital transformation.