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Inhaled Nanobodies Found to Prevent and Effectively Treat Severe COVID-19 In Hamsters

Covid-19 breath test could give you results in 60 seconds Finding a powerful drug and an efficient method to deliver it, has been the biggest challenge in the development of a faultless therapeutic strategy to combat COVID-19. Providing a potential treatment option, a new study has shown that inhalable nanobodies that target the SARS-CoV-2 coronavirus spike protein can help prevent and treat severe cases of the disease. Scientists from the University of Pittsburgh, using a hamster model, demonstrated that low doses of an inhalable (or aerosolized) nanobody called Pittsburgh inhalable Nanobody-21 (PiN-21) can prevent and treat acute COVID-19. This is the first time that the nanobodies which are similar to monoclonal antibodies (only smaller in size and more stable) have been tested for treatment via inhalation against coronavirus infections in a pre-clinical model.

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