Published 01 March 2021
It’s now been 3.5 years since I last wrote anything about testicular germ cell tumors and ongoing clinical trials.
1 Although we still cure most men afflicted with this disease, we have not made any major new therapeutic advancements since I wrote that last article. Approximately, 15-20% of patients with metastatic germ cell tumors will relapse following initial chemotherapy. Even in this situation, approximately 50% can still be cured with salvage treatments, either with more conventional cisplatin-based chemotherapy or with high-dose chemotherapy and autologous stem cell rescue.
2-4 However, patients with cisplatin-refractory disease or progressive disease following high-dose salvage chemotherapy and autologous stem cell rescue, harbor an extremely dim prognosis. In these situations, palliative chemotherapy, with regimens containing oxaliplatin, is limited in efficacy, and targeted biologic therapies have also shown limited efficacy.
UW study: About 30% of people who get coronavirus experience long haul symptoms By Becca Savransky, SeattlePI
Over the past year, more than 300,000 people across Washington have had COVID-19.
Only a fraction of those cases resulted in hospitalizations and deaths, but the lingering impacts of the virus are continuing to affect the lives of even people who didn t have severe cases.
According to a study from University of Washington researchers, about 30% of the people enrolled in the study experienced long-haul symptoms after getting COVID-19, reporting worse health and quality of life. About 8% said it went further: They weren t able to do normal tasks, such as lift heavy objects, or stand or walk unassisted for more than a short period of time, according to a news release.
Exercise has long been a potential way to reduce migraine triggers, but a new study suggests it could be an especially effective with triggers such stress, depression and trouble sleeping.
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