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Temple, Case Western scientists receive $3 million NIH grant to study pathway behind heart failure

Temple, Case Western scientists receive $3 million NIH grant to study pathway behind heart failure Like a bad water pump that fails to circulate coolant in a car engine, a failing heart struggles to pump blood through the body, causing symptoms of fatigue, shortness of breath, and swelling in the legs and feet. As heart failure progresses, the heart itself becomes increasingly unable to contract effectively, owing to changes in the molecules that control the heart, particularly a small gaseous molecule called nitric oxide. Nitric oxide is carried by red blood cells and acts as a signal to relax arteries and increase blood flow to heart tissue. It is also produced within heart cells, where it chemically combines with proteins in a process known as S-nitrosylation. More than 20,000 known S-nitrosylation events turn proteins on or off, including proteins that make up the heart s beta-adrenergic receptor (βAR) system - the system that regulates the fight-or-flight response that

Providers of underserved communities work toward equitable vaccine distribution

Providers of underserved communities work toward equitable vaccine distribution
crainscleveland.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from crainscleveland.com Daily Mail and Mail on Sunday newspapers.

Research by doctors in Ohio shows weight gain may help you live longer

Research by doctors in Ohio shows weight gain may help you live longer New research by doctors at the Ohio State University shows slowly adding on pounds as you age may actually help you live longer. By: WEWS Staff and last updated 2021-02-19 15:27:16-05 CLEVELAND — We know health risks associated with obesity include high blood pressure, heart disease and diabetes to name a few. But new research shows slowly adding on pounds as you age may actually help you live longer. Researchers at The Ohio State University reviewed the medical histories of more than 8,000 parents and children, which included tracking their body mass index. They found patients who started with a normal BMI, adding small amounts of weight as they aged, survived the longest.

Psychology and Emotions of Sex After Menopause

Maria Petrishina/Getty Images Ask a woman in her 50s what some of the most uncomfortable symptoms of menopause are, and she’ll likely say hot flashes or night sweats. While this may be true, there are other, less commonly discussed symptoms that tend to be even more bothersome, not to mention permanent. Some of these potentially life-altering symptoms can include intense vaginal dryness and pain with penetration; urgency and pain with urination; and overall feelings of genitourinary burning and irritation. Called genitourinary syndrome of menopause (GSM), this constellation of symptoms affects as many as 27 to 84 percent of post-menopausal women and can “significantly impair health, sexual function, and quality of life,” according to a study published in September 2020 in the journal

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