Bone Loss by Anastrozole may Reverse After Stopping It by Angela Mohan on January 22, 2021 at 12:25 PM
Anastrozole is a hormone treatment recommended by NICE to prevent breast cancer in high-risk postmenopausal women.
The results, published in the
British Journal of Cancer, are from a sub-study of 1,410 women from the International Breast cancer Intervention Study (IBIS-II) which investigated bone density in women who had completed anastrozole treatment.
At the seven year mark, two years after women stopped treatment, the study found that those with weakened bones experienced an increase in bone density at the lumbar spine. The increase did not occur at the total hip. The results suggest that decreased bone mineral density due to anastrozole treatment improves after anastrozole treatment is stopped.