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The inactivated vaccine, CoronaVac, proved effective in combatting COVID-19 in the city of Manaus, Brazil, where the highly transmissible P.1 variant emerged and has devastated the local population, researchers from Brazil and the Yale School of Public Health have found.
CoronaVac was shown to be 50% effective in preventing illness 14 days after administration of the first dose in its two-dose schedule. The study was conducted among nearly 70,000 health care workers in Manaus, which was the epicenter for the emergence of the P.1 variant.
It is the first study to evaluate the effectiveness of a COVID-19 vaccine in places where P.1, often referred to as the “Brazilian variant,” is widespread. Data will continue to be collected over the next few weeks to determine CoronaVac’s effectiveness after the second dose.
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