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The Medical Minute: What to expect post-vaccine Hilda Mantelmacher receives her first COVID-19 vaccination from Sister Mary Vu at Penn State Health Holy Spirit Medical Center. Image: Penn State Health The Medical Minute: What to expect post-vaccine February 17, 2021 HERSHEY, Pa. What if it makes me sick? What if it doesn’t work? How long will it protect me? For some people, anxiety over what may happen after they get the COVID-19 vaccine seems to almost outweigh the relief of getting protected. “People are approaching this vaccine with more hesitation because it was approved quickly, but that really just speaks to how far we have come in vaccinology,” said Dr. Mohammad Y. Ali, infectious disease doctor with Penn State Health Holy Spirit Medical Center. “This vaccine went through all the same rigors and reviews by independent data and safety committees as any other vaccine. No corners were cut.”

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