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NSAIDs Might Exacerbate orSuppressCOVID-19Depending on Timing, Mouse Study Suggests
New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the
Journal of Virology, a publication of the American Society for Microbiology.
The research is important because “NSAIDs are arguably the most commonly used anti-inflammatory medications,” said principal investigator Craig B. Wilen, Assistant Professor of Laboratory Medicine and Immunology, Yale University School of Medicine.
In addition to taking NSAIDs for chronic conditions such as arthritis, people take them “for shorter periods of time during infections, and [during] acute inflammation as experienced with COVID-19, and for side effects from vaccination, such as soreness, fever, and malaise,” said Dr. Wilen. “Our work suggests that the NSAID meloxicam dampens the immune response to SARS-C
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Washington, DC - January 22, 2021 - New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the
Journal of Virology, a publication of the American Society for Microbiology.
The research is important because NSAIDs are arguably the most commonly used anti-inflammatory medications, said principal investigator Craig B. Wilen, Assistant Professor of Laboratory Medicine and Immunology, Yale University School of Medicine.
In addition to taking NSAIDs for chronic conditions such as arthritis, people take them for shorter periods of time during infections, and [during] acute inflammation as experienced with COVID-19, and for side effects from vaccination, such as soreness, fever, and malaise, said Dr. Wilen. Our work suggests that the NSAID meloxicam dampens the immune response to SARS-CoV-2 infection.
Ryan Caron King / Connecticut Public
So far, tens of thousands of Connecticut residents have already received the COVID-19 vaccine. Yet nationally, vaccine rollout has been going slower than experts had hoped.
This hour, we hear from reporters about how policies have shaped vaccine availability. And we get answers from a doctor about the science behind the shot.
What questions do you have about the rollout of the COVID-19 vaccine?
First, a group of frontline workers have written a book about their experiences during the COVID-19 pandemic. We hear from one of them.
GUESTS:
Nicole Leonard - Health care reporter for Connecticut Public Radio
SAN FRANCISCO (KGO) A Bay Area company is working with the CDC to identify cases of the new coronavirus variant in the United States.
The more contagious variant, which was first observed in the United Kingdom, has already been detected in eight U.S. states, including California.
San Mateo-based Helix has partnered with Illumina to sequence the genetic material from positive COVID-19 tests, hoping to more quickly identify areas where the variant is spreading. Viral sequencing or viral surveillance is one of the tools we have not used as much as we should have during the pandemic, said James Lu, President of Helix.