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Medical practitioners are a step closer to improving treatment of people who need organ transplants, with new research from The University of Western Australia providing important insights into how immune cells respond to transplants.
Organ transplants are the final treatment option for many patients with end-stage diseases. However, despite improvements in the short-term, long-term survival rates of patients is low. This is primarily due to chronic rejection, caused by a long-term, uncontrollable immune response against the transplanted organ.
Clinical Professor Michaela Lucas from the UWA Medical School, senior author of the study published today in Cell Reports, said the immune system, which normally keeps us safe from infection, becomes harmful after transplantation as it recognises the transplanted organ as a foreign object.
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