COVID-19 Disease Severity May Be Driven by Antibody Responses
February 22, 2021
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COVID-19’s wide range of symptoms has been a particularly challenging piece of the disease’s puzzle to figure out. For children, the situation is even more complicated as they almost exclusively experience mild or asymptomatic COVID-19. But children who contract COVID-19 are at risk for a rare but serious syndrome called multisystem inflammatory syndrome in children (MIS-C). Severe cases of MIS-C can lead to cardiac disease and ventricular failure and require hospitalization and intense medical support.
In a recent study, researchers identified immune mechanisms that result in these disparate clinical phenotypes in children could provide critical insights into COVID-19 pathogenesis. More specifically, they found specific types of antibodies that may be driving these different responses, including one specific to severe disease in adults and another specific to MIS-C in children.
Symptoms of novel coronavirus vary from person to person on the basis of age, gender, co-morbidities, among other factors.Hence, a new study aims to find out why Covid-19 can lead to such distinctly d