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Researchers develop direct-acting antiviral to treat COVID-19

Date Time Researchers develop direct-acting antiviral to treat COVID-19 The Griffith University COVID-19 antiviral research team Professor Kevin Morris, Dr Adi Idris, Professor Nigel McMillan, Dr Arron Supramanin and Mr Yusif Idres. An international team of scientists from Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment centre for cancer, diabetes and other life-threatening diseases in the US, has developed an experimental direct-acting antiviral therapy to treat COVID-19. Traditional antivirals reduce symptoms and help people recover earlier. Examples include Tamiflu®, zanamivir and remdesivir. This next-generation antiviral approach used gene-silencing RNA technology called siRNA (small-interfering RNA) to attack the virus’ genome directly, which stops the virus from replicating, as well as lipid nanoparticles designed at Griffith University and City of Hope to deliver the siRNA to the lungs, the critical si

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