Researchers from Queen Mary University of London, have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.
CEACAM7 : Novel protein may improve safety of therapy for pancreatic cancer
This is an exciting development, said John Marshall, Professor from Queen Mary University of London
Saturday January 23, 2021 12:45 PM, IANS
London: Researchers have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.
Using this protein as a target, the team successfully created a CAR T cell therapy a type of immunotherapy that killed pancreatic cancer cells in a pre-clinical model. This is an exciting development, said John Marshall, Professor from Queen Mary University of London. Finding that CEACAM7 allows us to kill pancreatic cancer cells specifically with CAR T cells while having no significant toxicity in non-tumour tissues, gives us hope that this strategy could be effective in the future, Marshall added.
LONDON
Researchers have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.
Using this protein as a target, the team successfully created a C
E-Mail
A study by researchers from Queen Mary University of London shows that bone loss known to be associated with the use of the breast cancer prevention drug Anastrozole partially reverses, particularly at the lumbar spine, after stopping treatment.
Anastrozole is a hormone treatment recommended by NICE to prevent breast cancer in high-risk postmenopausal women.
The results, published in the
British Journal of Cancer, are from a sub-study of 1,410 women from the International Breast cancer Intervention Study (IBIS-II) which investigated bone density in women who had completed anastrozole treatment.
At the seven year mark, two years after women stopped treatment, the study found that those with weakened bones experienced an increase in bone density at the lumbar spine. The increase did not occur at the total hip. The results suggest that decreased bone mineral density due to anastrozole treatment improves after anastrozole treatment is stopped.