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Exclusive: Two variants have merged into heavily mutated coronavirus

Xinhua/Shutterstock (11701695a) Two variants of the SARS-CoV-2 coronavirus that causes covid-19 have combined their genomes to form a heavily mutated hybrid version of the virus. The “recombination” event was discovered in a virus sample in California, provoking warnings that we may be poised to enter a new phase of the pandemic. The hybrid virus is the result of recombination of the highly transmissible B.1.1.7 variant discovered in the UK and the B.1.429 variant that originated in California and which may be responsible for a recent wave of cases in Los Angeles because it carries a mutation making it resistant to some antibodies.

What you need to know about the new variant of coronavirus in the UK

Tolga Akmen/WPA Pool/Getty Image Many countries have closed their borders to people leaving the UK due to the rapid spread within the country of a new variant of the coronavirus that might be more transmissible. Meanwhile, South Africa is also reporting the spread of another new variant. Here’s what you need to know. What do we know about the new UK variant so far? B.1.1.7, as it is known, has 17 mutations compared with the original SARS-CoV-2 virus first discovered in Wuhan, China, including eight that may change the shape of the outer spike protein. Many of these mutations have been found before, but to have so many in a single virus is unusual. It was first sequenced in the UK on 20 September, but only caught the attention of scientists on 8 December, when they were looking for reasons for the rapid growth of cases in south-east England. On 14 December, the UK’s health minister, Matt Hancock, told parliament that a new variant that seems to spread faster had been identified

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