National Cancer Research Center (CNIO) It has been discovered how certain proteins ensure
Repair errors caused by DNA during replication. Use electronic cryoscopy to check,
Rafael Fernandez Leiro Make visible
Protein mutation, Also known as the “gatekeeper” of our genome, which allows them to describe how this single protein coordinates this important DNA repair process from start to finish.
The research is related to
Med Lammers, Leman University Medical Center, LUMC (Netherlands) and
Titia Sixma, From the Netherlands Cancer Institute and Oncode Research Institute.Their results are published in
Natural structure and molecular biology.
Between different stages
Cell division There is DNA replication, during which DNA polymerase replicates the genetic information of the cell to transfer it to daughter cells. Although the mechanism is very precise, errors occasionally occur. These errors must be repaired, otherwise it will cause tumors.