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UTSW researchers discover how vitamin A enters immune cells in the intestines

Immunologists and geneticists at UT Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines – findings that could offer insight to treat digestive diseases and perhaps help improve the efficacy of some vaccines.

Antibacterial immunity may change in the intestines based on circadian cycle

Antibacterial immunity may change in the intestines based on circadian cycle The body s ability to prevent food poisoning by producing a natural antimicrobial compound increases during the day, when exposure to noxious bacteria is most likely, a new study by UT Southwestern scientists suggests. The findings, published online in Cell, could eventually lead to timed therapies and vaccination regimens designed to maximize this immune response. This study shows that our immune systems are not turned on all the time, which is an unexpected result. Our findings suggest that there are peak times in which the body is more primed to fight infections.

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