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Hassles with child car seats linked to unsafe child passenger behaviors

 E-Mail Parents who reported more hassles using a child car seat or booster seat - such as the child is uncomfortable or having to make multiple trips in a day - were less likely to follow recommendations from the American Academy of Pediatrics (AAP) on child passenger safety, according to a study published in the journal Academic Pediatrics. Researchers obtained information about transportation safety behaviors and 20 hassles when using child car seats among 238 socioeconomically and racially diverse parents of children 1 to 10 years of age. Eighty percent of parents reported at least a little bit of a problem with one or more of the hassles. On average, parents had a problem with five of the hassles. Parents who were not following the AAP recommendations indicated the hassles were bigger problems.

Flashy Results From Double Valve Switch Surgery for AVR Candidates

email article In experienced hands, the Ross procedure was associated with favorable short- and long-term outcomes in young patients requiring aortic valve replacement (AVR), according to a retrospective cohort study. Survival was 95.1% at 10 years 88.5% at 15 years among more than 1,400 adults undergoing the double-valve procedure at highly specialized centers, Mostafa Mokhles, MD, PhD, of Utrecht University Medical Center in The Netherlands, and colleagues reported. The Ross procedure continues to be the only living-valve alternative in young and middle-aged patients with a reported survival that compares with the general population well into the second postoperative decade, the group wrote in

TRADING UPDATES: Chariot expects gas in Morocco; Redx wants CFO in US

TRADING UPDATES: Chariot expects gas in Morocco; Redx wants CFO in US
lse.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from lse.co.uk Daily Mail and Mail on Sunday newspapers.

A region within GLI1 gene could potentially be targeted as cancer treatment

A region within GLI1 gene could potentially be targeted as cancer treatment Scientists from the Stanley Manne Children s Research Institute at Ann & Robert H. Lurie Children s Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene s expression. These findings, published in the journal Stem Cells, imply that this region within GLI1 could potentially be targeted as cancer treatment, since turning off GLI1 would interrupt excessive cell division characteristic of cancer. From previous research, we know that GLI1 drives the unrelenting cell proliferation that is responsible for many cancers, and that this gene also stimulates its own expression. We established in living human embryonic stem cells that removing the GLI1 regulatory region eliminated GLI1 expression and halted its activity. These findings are promising and could point to a therapeutic target for cancer.

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