Photo: Matt Artz.
For nearly 30 years, the hunt for a cure for Alzheimer’s disease has focused on a protein called beta-amyloid. Amyloid, the hypothesis goes, builds up inside the brain to bring about this memory-robbing disorder, which afflicts some 47 million people worldwide.
Billions of dollars have poured into developing therapies aimed at reducing amyloid – thus far, to no avail. Trials of anti-amyloid treatments have repeatedly failed to help patients, sparking a reckoning among the field’s leaders.
All along, some researchers have toiled in the relative shadows, developing potential strategies that target other aspects of cells that go awry in Alzheimer’s: molecular pathways that regulate energy production, or clean up cellular debris, or regulate the flow of calcium, an ion critical to nerve cell function. And increasingly, some of these scientists have focused on what they suspect may be another, more central factor in Alzheimer’s and other dementias: dysfuncti
Katherine Blanner
Originally published on February 4, 2021 8:07 am
Sam Goodwin s first day in captivity was one of his worst. This was the point where I was incredibly terrified, he recalls about his ordeal. I felt like I had committed suicide but I was still alive.
A few hours earlier, on May 25, 2019, Goodwin was detained at a Syrian army checkpoint in the northeast part of the country. A truck pulled up and two armed men jumped out and told me to get inside. I did not have a choice, Goodwin says.
Goodwin, from St. Louis, was 30 when he was trapped in Syria s notoriously brutal prison system for 62 days. He s one of the few Americans who have been there and now, after his family and Lebanese intermediaries helped secure his release, he s telling his story.
Charter Communications Promotes Jessica Fischer To Executive Vice President, Finance
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STAMFORD, Conn., Feb. 4, 2021 /PRNewswire/ Charter Communications, Inc. (NASDAQ: CHTR) today announced that Jessica Fischer has been promoted to Executive Vice President, Finance from her current role as Senior Vice President, Finance and Treasurer. With this promotion, Fischer adds oversight of Procurement, Investor Relations, Internal Audit and Corporate Planning. Jessica s experience and ability to translate complex financial operations and transactional concepts into commercial plans have been an asset to Charter through the company s recent integration and subsequent successes, said Christopher Winfrey, Chief Financial Officer. With her strong leadership, financial communication skills and these additional responsibilities, she will play an even greater role in the company s future.
Jessica Guynn and Brent Schrotenboer, USA TODAY
Published
2:19 pm UTC Feb. 4, 2021
Editors Note: Kenneth Frazier, the CEO of pharmaceutical giant Merck, announced on Feb. 4, 2021, that he plans to step down from his post this June. Frazier is Black.
Nike has been talking this talk for the past quarter century: Diversity, inclusion, equality.
The company s ads, which famously encouraged America to Just Do It, have celebrated disabled athletes, female participation in sports and Colin Kaepernick, the outcast NFL player who protested racial injustice in 2016.
This year, after George Floyd, a Black man, died under the knee of a white policeman in Minneapolis, Nike announced a $40 million commitment to the Black community, declaring that it will never stop striving to role model how a diverse company acts.” Nike even has three Black directors on its governing board of 12.
Katherine Blanner
Originally published on February 4, 2021 10:07 am
Sam Goodwin s first day in captivity was one of his worst. This was the point where I was incredibly terrified, he recalls about his ordeal. I felt like I had committed suicide but I was still alive.
A few hours earlier, on May 25, 2019, Goodwin was detained at a Syrian army checkpoint in the northeast part of the country. A truck pulled up and two armed men jumped out and told me to get inside. I did not have a choice, Goodwin says.
Goodwin, from St. Louis, was 30 when he was trapped in Syria s notoriously brutal prison system for 62 days. He s one of the few Americans who have been there and now, after his family and Lebanese intermediaries helped secure his release, he s telling his story.