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Marine Natural Products Identified with Potential to Treat Lethal RNA Viruses

Marine Natural Products Identified with Potential to Treat Lethal RNA Viruses Russia. Shaded relief map of Russian Federation, with rivers, major urban areas. Surrounding territory greyed out. Colored according to vegetation. January 8, 2021 Three RNA virus families have been responsible for epidemics and pandemics throughout recorded human history. Scientists at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego, have broken down the biology, genomic makeup, life histories, and key drug targets of these three viral families. The authors also identified structurally diverse natural compounds in the marine ecology that could be used to develop antiviral therapeutics with the potential to disrupt the spread of these notorious viruses and highlight possible treatment strategies.

Could Natural Products Help Us Beat COVID-19 Virus?

Could Natural Products Help Us Beat COVID-19 Virus? Review of the life histories of RNA viruses, their genetics, and the compounds that could disrupt them offers hope for curtailment of future pandemics January 8, 2021 Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products compounds produced in nature with the potential to disrupt their spread. Journal of Natural Products, marine chemists Mitchell Christy, Yoshinori Uekusa, and William Gerwick, and immunologist Lena Gerwick describe the basic biology of three families of RNA viruses and how they infect human cells. These viruses use RNA instead of DNA to store their genetic information, a trait that helps them to evolve quickly. The team then describes the natural produ

Researchers identify natural products with potential to disrupt viral spread

Researchers identify natural products with potential to disrupt viral spread Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products - compounds produced in nature - with the potential to disrupt their spread. In a review appearing in the Journal of Natural Products, marine chemists Mitchell Christy, Yoshinori Uekusa, and William Gerwick, and immunologist Lena Gerwick describe the basic biology of three families of RNA viruses and how they infect human cells. These viruses use RNA instead of DNA to store their genetic information, a trait that helps them to evolve quickly. The team then describes the natural products that have been shown to have capabilities to inhibit them, highlighting possible treatment strategies.

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