E-Mail
BOSTON - Concerns about fertility often influence how young women with breast cancer approach treatment decisions and are a reason for forgoing or delaying hormone-blocking therapy, a new study by Dana-Farber Cancer Institute investigators shows.
The findings, published online today by the journal
Cancer, reinforce the need for physicians to talk with patients about their fertility-related priorities and address them in treatment plans, the study authors write. Such conversations are important not only at the start of treatment but during its entire course, as patients goals and preferences may change over time. Young women with breast cancer face unique challenges, including issues surrounding fertility, says the study s lead author Tal Sella, MD, of Dana-Farber. For many premenopausal women with hormone receptor-positive breast cancer, long-term endocrine therapy [which blocks hormones that feed the cancer s growth] may prevent patients from having children while
Date Time
Study dives deeper into genetic differences between modern and archaic humans
Researchers examined 14,000 genetic differences between modern humans and our most recent ancestors at a new level of detail. They found that differences in gene activation – not just genetic code – could underlie evolution of the brain and vocal tract. By Taylor Kubota
A genome by itself is like a recipe without a chef – full of important information, but in need of interpretation. So, even though we have sequenced genomes of our nearest extinct relatives – the Neanderthals and the Denisovans – there remain many unknowns regarding how differences in our genomes actually lead to differences in physical traits.
E-Mail
A genome by itself is like a recipe without a chef - full of important information, but in need of interpretation. So, even though we have sequenced genomes of our nearest extinct relatives - the Neanderthals and the Denisovans - there remain many unknowns regarding how differences in our genomes actually lead to differences in physical traits. When we re looking at archaic genomes, we don t have all the layers and marks that we usually have in samples from present-day individuals that help us interpret regulation in the genome, like RNA or cell structure, said David Gokhman, a postdoctoral fellow in biology at Stanford University.
A new perspective on the genomes of archaic humans eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.