Study reveals how non-alcoholic fatty liver disease can develop into a life-threatening complication
Researchers revealed how non-alcoholic fatty liver disease can develop into a life-threatening complication. Their discovery will accelerate the search for therapeutic solutions. The study was led by Helmholtz Zentrum München in collaboration with the Heidelberg University Hospital and the German Center for Diabetes Research.
Non-alcoholic fatty liver disease is the most common liver disorder worldwide and is present in approximately 25 percent of the world s population. Over 90 percent of obese, 60 percent of diabetic, and up to 20 percent of normal-weight people develop it. A key feature of the condition is the accumulation of fat in the liver. A liver can remain fatty without disturbing normal function; however, fat accumulations may progress into a so-called non-alcoholic steatohepatitis - an aggressive form of the non-alcoholic fatty liver disease combined with inflammation an
New ‘nomogram’ opens the door to improved personalized treatments, UCLA-led study shows
UCLA
Based on the study, researchers also created an online risk calculator that forecasts the probability of overall and progression-free survival in response to LuPSMA. Denise Heady |
July 8, 2021
A new prognostic tool developed by researchers from the UCLA Jonsson Comprehensive Cancer Center and five other institutions helps predict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy.
The tool, described in a study published today in Lancet Oncology, analyzes a wide spectrum of imaging and clinical data and is intended to assist physicians considering treating patients with Lutetium-177 prostate-specific membrane antigen, or LuPSMA.
Tool helps predicts who will respond best to targeted prostate cancer therapy scienceblog.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scienceblog.com Daily Mail and Mail on Sunday newspapers.
Molecular imaging can improve therapeutic management of pancreatic ductal adenocarcinomas
For patients with pancreatic ductal adenocarcinomas (PDAC), molecular imaging can improve staging and clinical management of the disease, according to research published in the June issue of
The Journal of Nuclear Medicine. In a retrospective study of PDAC patients, the addition of PET/CT imaging with 68Ga-FAPI led to restaging of disease in more than half of the patients, most notably in those with local recurrence.
PDAC is a highly lethal cancer, with a five-year survival rate of less than 10 percent. Optimal imaging of PDAC is crucial for accurate initial TNM (tumor, node, metastases) staging and selection of the primary treatment. Follow-up imaging is also important to accurately detect local recurrence or metastatic spread as early and as completely as possible.
Princess Máxima Center and German top centers embark on childhood cancer research collaboration
The Princess Máxima Center for pediatric oncology is to embark on a close collaboration with German top centers in Heidelberg in the field of childhood cancer research. With this strategic collaboration, the Dutch Princess Máxima Center and the German Hopp-KiTZ childhood cancer center aim to accelerate developments toward even better treatment options for children with cancer.
With this Twinning Program , the Princess Máxima Center, the Hopp Children s Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ) and the Heidelberg University Hospital (UKHD) are joining forces as centers of excellence in the field of pediatric cancer research.