Transcripts For ALJAZ The Stream 20240711

Ready to confront our adversaries, and not reject our allies ready to stand up for our values. Just ahead of bidens announcement, the Dow Jones Stock index went above 30000 points for the 1st time ever. Shortly after trading opened the market search followers, news of the coronavirus vaccines and bidens transition. But in a brief white house appearance, President Donald Trump took the credit. If european government says to grain Regional Forces have started to surrender 3 weeks after the army started its offensive in the northern region. It follows a deadline by Prime Minister for them to lay down their arms by wednesday, or face an attack on the regions capital. If they can a particular, his leadership says its fighting back, claiming its destroyed. An Ethiopian Military division, including a helicopter, and 2 tanks, a former militia leader in the democratic republic of congo has been sentenced to life in prison for war crimes. After a trial lasted 2 years, and to bury, also known as it was found guilty of murder, rape, sexual slavery, and enlisting child soldiers in north kivu province. He was tried by a special military court in the eastern city of goma. There are protests in france after the lower house of parliament gave initial approval to a controversial new law, limiting the right to film or photograph Police Officers that are or has been heavily criticized by rights group groups who say it could mean blurring the faces of Police Officers becomes the norm in news reports. Thats not stories to stay with us. The stream is next on whether 2021 will be here the World Congress coronavirus. I think there are plenty ok, you know, were seeing the home edition of the stream under the stairs in my house because it is 2020. We are in a global time to make, we have to learn so much of the past few months about because it 19. So here in the student wants to bring together some health professionals. Who could tell us what do we know now that we didnt know before . Talk about vaccines because theyre making headlines right now and what to expect in 2021 . I know you have questions. We are here for you. You can jump into the Comment Section of you tube, ask the questions and they can be part of todays show. Well, we have doctors in the house, we have medical professionals in the house. Its so good to have you back. Can you do your official introduction to the well tell everybody who you are in mind . The stream, viewers who may have seen you before. Thank you for having me on the show today. So i finds a bit of a doctor. I work in intensive care and emergency medicine by im also a journalist and ive written quite a few pieces recently on the Economic Impact of chronic are somewhat good to have evacuate kiko. Really nice to see you. Can you introduce yourself to i would its tell them he, while egypt. Thank you for having me on your cell. My name is actually, im a professor of immunology at the Yale University school of medicine. My lab studies the immune response to cover mounting and another doctor, you have krishna was in with us on the strain krishna. Introduce yourself to a global audience. Tell them what eating are good to be with you. Im krishna like mark from a position based on you can a versity and have the pleasure of leading the Global Health innovation center. Here in due course, we try to harness innovation to address health and Health Care Challenges including killed it. Welcome everybody. None of you would have missed the headlines recently about vaccines. And so i want to show our audience the 3 vaccines that are making nice right now, alive and making news. So lets start with the phase of 195 percent efficacy thought t dollars is expected types of it. So thats the fines of one, madonna. 94. 00 play fight the same efficacy. And it may cost somewhere between 25 and 37 dollars and inflation only ask, just send neka up to 90 percent efficacy sunni dollars and maximum cost is 1. 00 is way, way, way out of those doing the research on which you pick. Im lying. I think its really difficult question to answer that particular in terms of the data thats available at the moment. Not i might annoy a lot has been provided towards us, but its important to also look at like the history of Drug Companies in terms of how theyve actually impacted economies before. So in 2007, for example, pfizer was voted as the least reputable Pharmaceutical Company of the Big Companies out there. And is theyve been, theyve had quite a lot like 4 complaints, unlike in 2009 that had the biggest education against them. So there are times where john companies, especially in something that is so marketable. So i guess economically beneficial for a company where the whole world requires a chronic virus vaccine for them to maybe, you know, cut corners or try to jumps so and shortcuts. So for me to say which one am i going to trust . Now its difficult to answer that question. Its more of, lets wait for the data to come out before we can from the start say which one of those 3 is one of the most exciting kiko. Just looking at these 3, can you tell us that if thats true, the fine is a madonna and astra zeneca because at some point, either in the next few months or the next 6 months, people are going to be faced with a choice. Maybe they wont have a choice, maybe they just have to take one of them. Whats the difference between size of, for instance, the fight of axing . What should we know about that one . So the fires are in the modern or vaccines are the m. R. I. Vaccines. What that means is its taking the blueprint to make a protein called the spike protein, which is the target of the immune response to sars coronavirus 2, which causes the cove in 1000 disease. And thats introduced into the cell by lipitor capsule. And its our own cells that make the proteins, the spike proteins that become the target of on to bodies and t. Cells. The astra zeneca vaccine is a viral vectored vaccine, which means that were using the ad in our virus as a trojan horse to deliver the material inside the cell. And again, its the host cell that makes the protein, the spike protein that becomes the target of antibodies, intisar, s. So all of these things are, you know, have a very high efficacy so far, and im very excited about the let me just go to abdullah. Abdullah and adeline or new chief says, whose duty is it to conduct random, independent tests of the components of the vaccines because hes really concerned about transparency. Who is that something that using averages . I want to check the data and make sure its ok. Whose responsibility is it to do that . Well, i guess its part of the whole process of peer review research normally and its something thats not so rushed where Drug Companies trying to produce a product all go through various phases of research and admitted to different journals where other people who are peers of who work in the same field will go through the recession, the data, and then come to a conclusion whether or not their senses feasible or not feasible on a good through various stages. So there is always background checks that can happen. But in this, i guess more of a rushed process. Corners are being cut even when it comes towards the f. D. A. Or nice in the u. K. There are there are because its, theyre looking for emergency approval. What is it good, isnt it . Or as much scrutiny, what are the coolness, akiko, do you agree that there could, as you will have you sitting there with excitement and a medicine that i think the consequence . Well, corners are being cut. Certainly the phase 3 trials are looking at safety and making sure that no adverse events are happening. And so far, none of these 3 companies have adverse event that would stop it from going forward. And obviously the efficacy data, these are called press releases, which means that the companies that are conducting the trials are putting out news in the form of press release as opposed to what on that wants to see. Whats instead, peer reviewed, or at least preprint version on the raw data. And now we havent seen those yet, but i believe those are forthcoming. I believe this is a scenario i dont, i didnt big. I should be projecting stary directly or viewers around the world. But a way out now and now to be christian. Well, we dont know enough and we are living through a real crisis around the world. And so i agree that data is incredibly important, but theres a strong role here for regulatory bodies as well. In addition to the peer review process, and so we have seen the f. D. A. And other regulators also step up and make sure that they are providing transparency as well as clear guidelines as to what they want to see from the data, including evidence the as well as safety and maybe to go back to your 1st question, but what excites me about that Scene Development is really all of the above. I dont think we can be in a position where we try to choose just one of these 3 candidates or even more that are coming online. We know that in the best case scenario, where all 3 of these vaccines are seen to be effective and get approved, that the total manufacturing capacity is about 5000000000. 00 doses by the end of 2021. More than a year from now. And more than 3000000000. 00, of those doses are already purchased and spoken for. So were going to have significant shortages. And what we really need to be thinking about is portfolio management. So how many different vaccines can we bring online and how quickly and make sure that the right type of vaccine is going to the right place at the right time . Question and u. B. E. Tweeted out just a few hours ago as i can see this beautifully hand on my laptop about how many doses will be available in 20202021. How many ricky people top. So were looking by next year at the now im just going to make a quick one to thank for 1000000000 doses that need. Its very quick to create mathematics. Christian, i have a question for you. This question comes from uganda and this is going to have an issue. When you look at uganda police, then what is the take for us to get . No right to do this. You plan to probably standing in the how im going to ensure the last minute we do not see him. Look at that in front of the scene. You need to get really feel as though this is nothing to be still and was the last of the season pass times frequent. Im going to have to do a problem because we need to ensure that people with my eyes, if nothing to see yet. Thank you. And im afraid, i think thats a really critical question. And i would say, where have platforms like kovacs, the world health organization, gavi and sappy have come together to really bring together a single platform to try to fill a tape equitable access around the world. And wonder really well now i know can i say sure, this weekend a medical well to things like psych scenes for affordable prices, low actually even free christian. Thats right. And so there is room there. Certainly for improvement. We need tens of billions of dollars more to be raised in this equitable way. And the idea that we might need ultra cold chain in places that are outside of cities, especially in low resource that ngs are going to be very difficult. Which is why getting the positive data on the Astra Zeneca Oxford vaccine, as well as some of the others that are in the late stage of pipeline is going to be really important. And in addition to kovacs, i think were starting to see things like the African Union and the africa c. D. C. Come together to protect your funding from across the continent so that they too can make purchases to cover their own populations. So we are starting to see some movement, but a long way to go, akiko, i feel, and im picking up from our online community, some hesitancy about taking the vaccine. This is sure c 100 on you say i want to take the vaccine, but part of me is worried about its safety. But mostly because other people afi is. So i dont know why. Ok, so thats all of us and protecting our fear is our concern. But we also tracked down rather who is in south africa. Shes in johannesburg, and shes been taking part in Oxford University trials. And she has a very different perspectives regarding taking a vaccine. Heres one thing i chose to take part in the south africa in aspen vaccine trial for the co, the 19 virus because i think its incredibly important to have days that is relevant to my local context. I also would like to believe that my taking who would, in some way, shape or form enable the people of my countries have access to the facts and when its finally improved. In terms of whether i will trust the vaccine when it is available. Absolutely. And i think partially this is involved by the fact that having been on the trial, ive been able to witness firsthand the different Safety Measures and the cautions that they take in to ensure that safe and effective akiko pick up on that. Yeah. So i think a lot of the sphere comes from the fact that the mit of axioms, for example, is a new platform that has not been approved for any other infectious diseases. Yet. However, there is very little to fear about any of these facts. And as i mentioned, the safety is number one and the woods are through there are trying, are people really paying attention to what kind of side effect they might have or what kind of adverse events that these volunteers that are taking the vaccine my suffer from and so far we have seen no concern nost of your concerns from any of these vaccines. And secondly, the m. R. D. Vaccine. Essentially what were doing is were just sort of telling the cells to make the virus protein that otherwise you would name it, you would make up on exposures. The virus. So sort of giving us a leg up 1st to produce our antibody before being exposed to the virus, gives us the ability to block and neutralize and really help us from getting severe diseases. So i think, i mean, i would be the 1st one to line up to get the vaccine if any of these things are approved. So i asked him, which one, which he pick, which one would he choose . Im tempted to do that 95 percent one efficacy, which one would you pick if you had a choice . Like i said, its no complicated. Depends on availability or should it be me that goes 1st to the other people, but b. But receive the vaccine for us. So were sure would i take that step that was to keep her because she i could go is very confident about this. Yes, lets lets, lets look at her for the hard question. Ok, go which one i would take any one of them because i like i said, theyre all been so far and safety concerns are, are not there and efficacy is pretty great for them. And 9594. 590 percent, these numbers might change as we test more and more people, but theyre going to hover around that range. So i dont think there is intrinsically anything that different about the efficacy of these 3 x. Means. Let me go to it for him. If we have missed it, but he has 2 questions for you, so well go straight to him and be great team if you could answer his questions, he would get i missed all those things. Getting in the business. Is me telling our physical problems or is a bigger countries . Yes, but a lot of the rivers he has. One of these he looks like is there the organization here is rather easy to do. You know, theres not a hoodie, lets go with that 2nd point 1st, are there any african or developing countries who are nightly to get the vaccine 1st . Krisna you pick that one . Well, i do think we are going to see more equitable distribution once. And some of these candidates become available in a more formal way. Every game is exactly right in that we have a core history around the world of ensuring equity in the way that we develop, evaluate, and then make available different innovations around the world. I think there have been attempts and new forms of art or ships related to coba, but also in ensuring that the way that the trials have been conducted include the diverse populations. And im hopeful though, i think it may be a bit of time before all countries get access to this vaccine when its available that at least will start to see some distribution early on. And hopefully early in 2021 is when we start to see distribution, not just in high income countries, but also in low and middle income countries. And in the 2nd question he added keep them going to give you this one. If you take the vaccine does not mean that you cant get coverage 19. So how the facts scenes are evaluated is such that they are looking for people who are either in a placebo versus the vaccine arm in getting symptomatic infection. So symptom symptomatic, plus the virus positive where the, whether you will be completely protected from ever getting infected or not, is not what theyre looking for. And so its possible that even the vaccinated you could get infection, but that does not lead to symptoms or severe disease. So ultimately what we want to do is to protect as many people as possible from getting sick from this infection. And thats the goal of these facts, things. Thank you for answering the questions. It was like as a spin around of questions, really appreciate that. Weve learned a lot and speaking of learning a lot, i want to remind you. I was looking on my laptop, the 2 occasions that we asked dr. Ahmed twats to be on asho. The 1st time was coronavirus. How can we protect our Health Care Heroes . That was in march, you know, every is banging their pots and pans in the u. K. And then the 2nd time was in may when we were just really worried about how are you doing, how are you managing . Because the cases for coronavirus had not necessarily dropped around the world. What have we learned from it in all of these months since then when you were on the front lines as one paycheck that you could actually see your mask . The marks of a mask on your face while you were doing this stream. What would you say is the most important lesson that weve learned, or youve learned, or your colleagues have learned in the past 8 months or so . I think in terms of the actual disease, weve been able to learn how to pick up the symptoms quite quite quickly. Whereas before, people come in with like the difficulty in breathing when really sure whats going on. But now we can just pick up without having to wait for the actual code that result to come back. You can kind of see the pattern thats developed to be like, yep, that ones code. That one isnt. And then i think for us, whats really important is to know when to start treatment and its always start treatment early. Thats it. With other diseases. Sometimes you kind of like, you know, you can wait it out a bit more. But with code, it is cool with start treatment early, and we also know the complications and for us to learn how to make it stop the spread. Thats probably, i think, i guess is that towards actually improving how we deal with this pandemic. If were able to stop the spread, less people are infected, whether thats preventative medicine through vaccines, by the moment this moment time, we dont have a bison to use that, we have to look at other ways to stop the spread. And now were seeing maybe 2nd, perhaps 30 wells, and angry thi, Northern Hemisphere going into winks at times. It seems like the cases what advice would you give us as a Global Community knowing what you know about dealing with because it 19 what is the same as what we were weve been saying for the past year. I guess its that this disease is real. Its affecting people, so you need to try to prevent as much as you can if you need to go out where the facemask like, where there is no reason feature where the face mask there dont change. Just studies are sure it doesnt actually cause suffocation. You can wear and breathe normally. So its things like that. And you know, if you dont have to go out, dont go out like you dont need to my precious office or risk contaminated others. But thats, i guess for us is the best way to understand and if you have symptoms stay at home like i did dont risk, it might just be the cold might just be the flu. It might be nothing that you have an aco that but why risk it is their home and protect those around you . I want to see them bring well more person into our conversation. This is clear and clear points out. The fact that weve been talking about vaccines for a big chunk of this show doesnt mean that curve at 19 would disappear yes. Over over the past, a resource in some excellent news about more than one vaccines being over 90 percent effective against sars kovi to this is not sufficient to halt the spread of the disease immediately. Next, a nation can only move at the same pace as manufacturing. They were simply dont have enough capacity to produce doses for the entire Adult Population within 2021. We also do not know if the vaccine is effective at stopping the transmission of the disease. Finally, immunity is built over the course of about 6 weeks, from the 1st dose of the vaccine. This means that it doesnt matter so much when the 1st person is vaccinated barrow when the last person is vaccinated and has been unity until then will have to have some control measures in place. When christian has such a good point, you pointed out how many billions of doses and already been purchased of various vaccines. But in terms of human behavior, what difference will these vaccines make in the next 6 months or so . What would 2021 begin to look like . Yeah, i think clear was exactly right and id say 2021 will be better than 2020, but thats a pretty low bar. We will not return to normal in the next year or 2 years. And youre right, vaccines are not going to be the Silver Bullet that get this out of this pandemic in the next 6 to 12 months. Even if we produced hands of billions of the summit was saying what weve learned is how to be functional as a Society Without a vaccine. And countries like new zealand, like taiwan and others have shown us that it feasible to be close to normal. If you take appropriate health measures, and weve also seen in parts of europe and the us, that this can be a horrible disease that an individual and a population level. If we dont do those things. While im optimistic about that Scene Development over the coming years, im also very scared for what were going to go through over the coming winter. Ive just spent the last 2 weeks in the hospital every day taking care of patients. And as i meant that this is very real and we need to take it very seriously, and we cant become complacent just because there may be light at the end of the tunnel. I want to leave everybody just as a reminder, because you can create huts with talking about sex scenes, but i want to leave you with some because 80 he is really to 2 on to sing or a couple of months spent. Hes got the night is young, the whole country image for those worst affected the road back to full health can be a long walk it. Hughes advised a month in an induced coma and 17 days on ventilation. Machines kept him alone leave as his body ceased to function. To see quite a while just looking out, it was difficult for medical point of view. Israel decision to talk to knowledge you today. Were not out of the woods yet, but frankly so much. And krishna and akiko for getting us up to date, what we know, what should we expect from vaccines and all of the questions you cheap as excellent questions as always. And we will continue to do updates and bring you news about covered 19 in vaccines as we waste in here on the stream. But for now, im signing off from the home Edition Studio because coverage 19. And i will see you next time. Thanks for watching everybody take Business Leaders desire to buy no brass. Paul Business Leaders does want to buy no brass. Paul france once had, a vast empire spanning several continents, but by the 1940, s. , the french were forced to confront reality. And to moms from dependence. On a fast part of a new documentary series, aljazeera looks at how the colonial unrest, room conflict a nonjury up and full scale war in indochina. Blood into his french to colonize ation on aljazeera. From the favelas of caracas. So the battlefields around also i would job is to get to the truth and empower people through knowledge. Ready hunan taylor in london, the top stories on our syria, joe biden is forging ahead with his preparations to take over as president as his margin of victory keeps growing. Hes just formally unveiled some of his top team of pennsylvania and nevada. Have become the latest states to certify him as the winner, the president elect was joined by the men and women. Hes picked to be his Foreign Policy and National Security chiefs. Its a team he says is ready to lead. The world comes after President Trump began to give way, allowing the official federal transition to begin with government funding and classified intelligence briefings. Its a team that