Analysis of Proteomics Helps to Identify Drug Targets by Angela Mohan on March 5, 2021 at 12:14 PM Proteomic analysis is a useful approach to identify potential novel therapeutic targets, as per the study in the journal Oncogene. The identification of "proteomic signatures" are associated with clinical measures of aggressive disease for seven cancer types studied. Some signatures were shared between different types of cancer and included cellular pathways of altered metabolism. Importantly, experimental results provided proof-of-concept that their proteomics analysis approach is a valuable strategy to identify potential therapeutic targets. "There are two notable aspects of this study. One is that we explored the proteomic landscape of cancer looking for proteins that were expressed in association with aggressive forms of cancer," said co-corresponding author Dr. Chad Creighton, professor of medicine and co-director of Cancer Bioinformatics at the Dan L Duncan Comprehensive Cancer Center at Baylor.