ASK THE ORTHOPAEDIC EXPERT DNB, D Orthopaedic with Fellowships in Joint Replacement Surgery as well as Arthroscopy and Sports Medicine, bringing solid and stable expertise to his field. ► I am a 52-year-old woman. I am borderline diabetic but have severe varicose veins problem in my left leg. Recently, I visited my doctor for knee pain and he asked me to undergo joint replacement surgery for both knees. Is it safe in my condition to undergo surgery? Yes, a person with varicose veins condition can undergo Total Knee Replacement (TKR) surgery. Though it is essential to check the grade of your varicose vein condition before undergoing the surgery.