AstraZeneca shortfall may hit vaccination of the over-70s And there are also worries about the effectiveness of the ‘game-changer’ vaccine in older people. The German media last night reported that government sources do not believe the AstraZeneca vaccine will get the approval of the European Medicines Agency (EMA) for use in over-65s. The vaccination of people over 70 has hit a major setback with concerns now that a shortfall in AstraZeneca supply will cause their vaccinations to be delayed. Pic: REUTERS/Dado Ruvic/Illustration/File Photo The shortfall of planned deliveries of the AstraZeneca vaccine, due to hit in March, has also sparked serious concerns about the rate at which older people will be able to get vaccinated.