Atomic-level structural models of enzymes provide disease in

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

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Amanda Gavin , Xueyong Zhu , Fangkun Luan , Ziqi Feng , Jeanne Matteson , Jenny Tran , Ian Wilson , David Nemazee , Linghang Peng , National Institutes Of Health , Department Of Immunology , Computational Biology At Scripps Research , Scripps Research Institute , Department Of Integrative Structural , Scripps Research , Meng Yuan , Integrative Structural , Computational Biology , Deli Huang , National Institutes , Skaggs Institute , Chemical Biology , Enzyme , Structural Biology , Lzheimer 39s Disease , Arthritis , Fell , Cytoplasm , Na , Immune System , Mmunology , Lupus , Lupus Erythematosus , Ucleic Acid , Ucleotide , Phosphatase , Research , Rheumatoid Arthritis ,