Cells Within the Center of a Tumor Are Most Likely To Metast

Cells Within the Center of a Tumor Are Most Likely To Metastasize


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Researchers from the Francis Crick Institute, Royal Marsden, UCL and Cruces University Hospital have found that cells from different parts of kidney tumours behave differently, and surprisingly, cells within the centre of a tumour are the most aggressive and have the highest chance of spreading around the body.
Cancers can spread to other parts of the body, with cells taking hold as secondary tumours which make the disease much harder to treat. Understanding the mechanics of this spread, a process called metastasis, could lead to new treatments that block this migration.
In their multidisciplinary study published today (17 May) in Nature Ecology and Evolution, scientists led by the Litchfield lab at UCL and the Turajlic, Swanton, and Bates labs at the Crick, analysed 756 cancer biopsy samples from different regions within tumours from the TRACERx Renal study.

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, Kevin Litchfield , Samra Turajlic , Cruces University Hospital , Crick Cancer Dynamics Laboratory , Cancer Institute , Francis Crick Institute , Royal Marsden , Nature Ecology , Cancer Dynamics Laboratory , Consultant Medical Oncologist , Chief Investigator , Nat Ecol , கெவின் லிட்ச்பீல்ட் , சிலுவைகள் பல்கலைக்கழகம் மருத்துவமனை , புற்றுநோய் நிறுவனம் , பிரான்சிஸ் கிரிக் நிறுவனம் , அரச மார்ஸ்டன் , இயற்கை சூழலியல் , ஆலோசகர் மருத்துவ புற்றுநோயியல் நிபுணர் , தலைமை புலனாய்வாளர் ,

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