Computational Modeling in Developmental Biology Image Credit: Tavarius/Shutterstock.com What is computational modeling? Computational modeling is the use of mathematics, physics, and computer science to create complex, dynamic models of systems based on multiple data points. The growth of sophisticated data-gathering technology such as wearable sensors and internet-connected medical devices has in part been responsible for the recent growth of the field. Computational modeling has been applied to several fields including weather forecasting, flight simulation, and earthquake simulations, as well as the biological sciences. Computational models in use today can provide data on a biological system at multiple levels. This type of modeling is known as multiscale modeling.