DOST usec for regional operations succumbs to cancer Share on email The Department of Science and Technology (DOST) announced that its undersecretary for regional operations, Brenda L. Nazareth-Manzano, has died after a long battle with cancer. It is with great sadness that we announce the passing of our DOST Undersecretary for Regional Operations Dr. Brenda L….Posted by Fortunato de la Peña on Wednesday, February 3, 2021 DOST secretary Fortunato “Boy” dela Pena said in his Facebook post that Nazareth-Manzano passed away at 10:43 a.m. on Thursday, Feb. 4. “The consummate public servant, she died with her boots on, ever the champion of regional development through science and technology. We will truly miss her passion, her friendship, ready smile and helping hand,” Dela Pena said in his post.