And heres your host dr coston they could top it. Imagine me writing this bike 3 times around the world i would surely have to see a mechanic to get a few paired sometimes not so hot and this is the distance our blood travels around on our bodies have are old times because of our optimism veins at a distance of more than 100000 kilometers and this is not all blood down as it helps us doctors to diagnose certain diseases sometimes even before a patient gets into. And thats why im here at berlins dept today this is where 65000000 lots and lots are examined every year the scientific Director Office all his english tell them he knows everything about it not he will tell us how few drops of it can tell us everything about all heart losers keep. Not testing is an essential part of modern medicine. Scientists are discovering more and more of the blood quality a full plate is doing research that the study Team Building on how to take cancer in the stage or to specifically target children. Nowadays were able to treat constipation anybody will eat with us. Of the good biopsies. For insisting his blood was like aspirin is for us today it was a cure for many things like behaving and blood against leprosy or drinking fresh schuman blood against seizures or just think about bloodletting to get rid of all the evil forces in the body well blood is not that creepy any war but its amazing what blood can do. The heart continuously pumps blood around the body up to 10000 liters flow through its chambers every day enough to fill 50 bathtubs. The largest artery is the aorta and its as thick as a garden hose while the tiny capella are easy a thinner than a human hair. They form a kind of transport network. And blood is the bodys Delivery Service it supplies the cells with everything they need like sugar ion fat oxygen and hormones. Blood flows through the arteries at speeds of up to 2 meters a 2nd. And on its way back to the heart it brings waste products from the body cells like c o 2 and urea. More than half the blood is made up a plasma which is mostly water. Some of the bloods components are made inside the bones. A yellow mary who contains he makes hope a attic tissue where billions of new blood cells are produced every day the different types of blood cells start off a stem cells through a process called cell differentiation they become white blood cells platelets and red blood cells and they all have completely different jobs. Blood platelets prepare the wounds white blood cells search the body for dangerous viruses bacteria and toxins certain white cells called plasma cells produce up to 2003 bodies a 2nd they target foreign substances in the body known as antigens to neutralize or destroy them red blood cells contain hemoglobin which binds to oxygen this is how blood gets its red color the more oxygen it contains the brighter the red. Blood is sometimes referred to as a liquid organ which is no exaggeration considering the many vital functions it performs. Im here with professor would have told by hes the scientific director of burlap thanks very very smart person youre a left physicians and a blast specialist so whats so fascinating about blood well a lot is a peculiar fluids a very very complex mixture and it reflects like a mirror or a Looking Glass the condition of a patient both pursue respect to health and disease and we can find out a great lots of informations about the patient so are there any alarms sides that you can see in the blood before the patient even have to see his symptoms yes you address the matter of early diagnostics or what would even be better of prevention in germany we take a chinese drop of blood from a newborn child and any law use it for markers of seaview diseases there are new methods in the lab like mass spectrometry where do you use most bitter. If you feel the use in the clinical lab is a quiet new development and mass spectrometry allow the identification and detection even of molecules which have been to this state unknown of course when the patient takes a rock which has potential side effects its essential to monitor the concentration. And since to date many new drugs are happily for the patients benefits introduced into therapy its essential that we in the lab are able to detect and to quantitatively measure these new drugs and this is feasible by the use of mass spectrometry are there any tests that everyone should take essential tests include for instance cholesterol since call a stall is a real important risk factor for coronary Heart Disease 2nd i would recommend to do basic testing for liver diseases kidney model function i would have a white and red blood count and for female patients i recommend to enter law is the iron concentration of the lot so if you dont want to see your g. P. There are some companies that offer blood tests over the internet what you think about this i personally have my serious reservations about blood testing over the counter without see it why is of a medical doctor or a general practitioner. The reason for this is that the test result must be interpreted and evaluated and this requires medical knowledge the interpretation of the symptoms to link the test results with the personal history of the patient the medication the symptoms and other medical conditions and this is really important to come to the right conclusion based on the test result always see you trape 1st except you know when the 1st blood transfusion was performed it was 1492 when the pope was sick so he did fresh blood and he was given that from 3 Young Children unfortunately 3 children died and the pope didnt get well the transfusions and routine procedure in medicine but theyre not without danger. Because al is about to have bypass surgery its a procedure with a high risk of blood loss and the house is understandably worried. Pretty frightened sure scott. Its Standard Practice to have blood reserves on hand during the procedure but the doctors here at the university in frankfurt are taking a different approach. Because of whats a warning to major operations are a bit like running a marathon so we get the patients ready the way people prepare for a sporting challenge and this is into in terms of hemorrhaging hemoglobin plays a big role due to the higher the hemoglobin levels ahead of an operation the more of a buffer you have if they drop during surgery. Thats the key factor in deciding if the patient needs a blood transfusion thats why the patients blood is fortified with iron before surgery and doctors establish if theres any likelihood of a coagulation disorder because a transfusion is always a risk. Of blood transfusion introduces a range of foreign cells its comparable to an organ transplant and hows immunological consequences fictive even a transfusion from the same law group doesnt rule out a defensive reaction like fever hemorrhage or nausea. But we know that you can give a patient too much blood and overtaxed their circulation it could even cause a problem an area deemer so its extremely important to be very careful and only give the patient the exact quantity they need. To keep in addition its better to err on the side of caution hospitals have developed patient blood management programs to prevent blood loss during and after surgery for example doctors can use whats called cell salvage during an operation thats a way of collecting the blood lost during the procedure. It can then be infused back into patients if necessary. They are also kept warm with heated blanket. Keeping the patient warm helps optimize blood coagulation so the patient loses less bludging surgery something of that 36. 00 degrees is the baseline temperature for blood platelet function platelets react to bleeding by clumping thereby initiating a blood clot. Researchers at the University Hospital in frankfurt have developed a small heart lung machine that helps limit blood loss after surgery lost can also be limited by taking smaller amounts of blood during tests. Patient blood management programs can help hospitals cut blood transfusions by 50 percent. They also ensure that hospitals have sufficient reserves for patients such as was left which we definitely will need donor blood. And was in the weve noticed that your hemoglobin levels are on the low side to meet him and. She requires a transfusion after her hip operation for some patients it can be a lifesaver so every drop of blood matters. Im still in burlap with professor. Black this also very important for the diagnosis of Rare Diseases can you give me some examples yes this example is for new kettle nuria it is c. S. Caused by order of amino acid metabolism. Children affected by the deceaseds suffer from damages of the brain and suffer from mental retardation if that is the this is the diagnosis early enough that children can develop normally through a diet and all this can be diagnosed from a very small drop of blood. If there is Something Special about. It is that its very closely connected to research can you leak some secrets what kind of research is going on yes. We are working quite hard. To improve and a little x. Of rai blood spots this means a drop of blood put onto a small paper card and draw it and it will ask why we are doing that the reason for this is that it may be difficult to transport liquids plot samples in some areas of graphical regions. And its much more easy to transport a dry lot spot on a cot in an envelope put into the mail a 2nd example is analytics and diagnostics to detect and to monitor or malfunction of Kidney Diseases or at Kidney Disease and here we develop new markers which allow and facilitate to properly estimate the degree of kidney malfunction many of my patients ask me if its possible to detect cancer in the blood so is it possible well Early Detection of cancer in the blood is a real challenge and with the exception of prostate specific antigen p. S. A. To my personal view we have no screening chill marker which allows Early Detection of cancer. But there are prospects that we will be able to develop such tests days on genetic or and epi genetic testing and bio chemical testing and possibly also based on liquid biopsy thanks so much for this interesting talk thank you it was my pleasure lets take a closer look on the test called the could pipe see. Its client youll feel a little jam but you know that already in this issue. Book so has come for a checkup so were still in just 2 more and were done. The blood test spares Cancer Patients a pain for risky procedure to extract tissue from the tumor a standard biopsy wasnt an option for her anyway. And is apparently living under there in the search all could positions in both the lungs that theyre hard to reach and she hopes this liquid biopsy will help or switch to a targeted medication and come off chemotherapy which affects the entire body. And i felt awful at the start of the chemo wreaked havoc really affected my blood values. The clinic thats treating belongs to and that work of experts by testing their tumor d. N. A. In the blood samples they can often determine which subtype of cancer the patient might have. Targeted medications have been developed for certain types of the disease including. In this. We might be able to give you medication in tablet form. But so far the medication has only been approved for Ovarian Cancer not for a trimmer in the long so like. You know. One day an oncologist will treat pretty much every type of tumor regardless of whether its Breast Cancer or Ovarian Cancer or Something Else the aim is to characterize tumor cells more and more precisely and to develop more drugs that allow us to move away from chemotherapy. That would be of great benefit to patients who would have less hair loss or other side effects all the problems you otherwise get dont happen when the therapy targets only the 2 marcels which helps patients quite a bit. Has been having chemotherapy for 5 years now and she still has her ups and downs. And i have a lot of support from my family my husband my daughter my grandkids they always pull me back up when i feel. Shes hoping the drug will soon be approved for her cancer too so she can switch to this targeted medication. Im gives dr claudia photographed at the Berlin Charity and youre performing the socalled liquid pipe see what thread currently modified asterix stuff on tissue socalled sections of pirates least. This collection and that can be difficult in patients with poor general conditions like Cancer Patients and status and nowadays we have the option to do this analysis that others off to more south Genetic Information on because biopsies so that means youre taking a blood sample of the patient and youre looking for d. N. A. Of that yourself right we start with the collection off a little mound of a lot that we isolate the d. N. A. From the patient which contains the Genetic Information of the benign cells and also information off your selves what kind of information do you gain from the spots in actually were looking for resistance mutations so this means were looking for changes in the Genetic Information of the tumor cell which lead to probably a progress of the tumor in the patient and so that we can change the therapy of the patient accordingly so does that mean that it helps you to find the right kind of. Just. Its a bit of both so actually you know we are of course hope that we can change the therapy of patients. In order to have a better chance for the patients and other any other advantages of method one is that it is minimal and there is nothing so you can probably do a kind of money tarring for the patients you can collect the blood. In serious and check if the resistance of cures and you can do it many times before you see a change in probably c t e r m i t. Right now youre performing this kind of examination of tumors so if you look into the future with other tumors you can do this examination you know this is a very promising method and very valid so we expect to have this kind of analysis for Breast Cancer and very near future thanks so much for the interesting talk this is a very modern method doctors are doing with the patients blood but doctors have been taking that from patients for centuries and theyre not just taking it theyre giving it back to the. Autologous one therapy is the treatment of disease by using a patients own blind. To begin with i found it a bit spooky the idea of having my blood taken twice a week and then getting it reinjected over a fairly long period of time. But claudia hoff gave it a try she suffered from herpes for a number of years and kept on getting blisters forming on her back at 1st she tried a conventional approach. As if it was my dermatologist prescribed antiviral drugs which i was supposed to take for 3 months. But fairly quickly after a few weeks it was obvious i wasnt tolerating it well. Michelle answers is familiar with the problem antiviral drugs can be an effective treatment against her peace but hes also found that for some patients alternative treatments work better such as calling this month therapy something hes researched himself at the shouty hospital in berlin. Says that it doesnt look at this for Cancer Treatment that dates back to antiquity in the past it was seen as magic the significance of blood also played a role nowadays autologous blood terror being also called also him a therapy is used in alternative medicine as a stimulation therapy designed to alter our modulating immune system. It affects my whole body and some cup of alaska than ive. Cloudy off began the treatment in the spring to start with samples of blood were taken from a vein in her arm over a period of weeks. Each time the blood that was removed was then immediately injected back into her gluteal muscle with a 2nd sterilized syringe with no additional processing. The whole blunt there of being involved gradually raising the dosage to 5 millimeters per session then reducing it again. How exactly does the therapy work. Is i guess the news of. Fresh blood drawn from a patients brain and reinjected into their muscles triggers a complex immune reaction that the details of this reaction have not yet been fully researched and understood but the reaction is triggered over and over we can boost it further by increasing the dosage which boost the stimulus to. The cereal application gives rise to a sort of training effect that stimulation the immune system and thereby improving the bodys immune competence is its author regulation but the one competence of those couples opposite studies appear to confirm the efficacy of autologous blood therapy. To any given site its a few studies have shown that its effective in treating hives or to cardio. Theres new research from a bomb for example that shows that terribly is also helpful with chronic fatigue. A clinical observation study at the shopping taney has also shown that its effective in treating her peace and the positive effect is still apparent a year after the treatment thats encouraging news for claudia hoff. Other forms of the treatment and follow some change to the blood before it has reinjected such as oxygenation ozone nation or the addition of homeopathic remedies designed to further stimulate the immune system as yet there are no scientific studies on this. During and after the antichrist blunt therapy claudia hopes condition did improve a bit she gets fewer lesters and they also clear up faster. I felt very good during the treatment. It was a positive experience much more so than i would have expected. That positive effect could be further boosted by a refresher round of treatment the treatment should always be done in a specialized practice hygene is of course essential. Cloudier half has in the meantime decided to go for a 2nd round of ontologies one therapy. I can see theres been a change so i feel it was worth it in the and and there was nothing spooky about it at all. Theres still no scientific proof that alter him with a repeat works so if you want to have a go with it 1st check with your g. P. Like us g. P. s always like your questions like i do. In good shape youre a Weekly Health show one that covers many aspects of health care we look at whats new in medical treatment nutrition fitness and beauty we discuss these topics and depth with specialists and offer you opportunities to pose your own question so get in touch. Thats enough for today see what i freak and so then lets all try to stay it good check. Thanks. Dana loesch loop economy. 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