Wednesday, December 16, 2020 EPA recently released its Fall 2020 Regulatory Plan and the Unified Agenda of Federal Regulatory and Deregulatory Actions (regulatory agenda), which includes several important updates to planned actions under the Toxic Substances Control Act (TSCA) (15 U.S.C. § 2601 et seq.), concerning section 5 pre-manufacture notification (PMN) content and review procedures, section 6 risk evaluation and management for existing chemicals, CBI claim procedures, risk evaluation fees, and chemical data collection. While the Biden administration may significantly change the regulatory agenda consistent with its priorities, below we summarize aspects of the current plan affecting chemical control regulation. New Chemical Reviews EPA confirmed its plans to propose a rule by May 2021 to revise the TSCA new chemical review regulations (40 C.F.R. Part 720). The revisions are intended to “align [EPA’s] processes and procedures with the new statutory requirements” for PMN decision-making from the Lautenberg Chemical Safety Act of 2016. The rule revisions also are intended to “improve the efficiency of EPA's review process” for PMNs. This will be accomplished by “increas[ing] the quality of information initially submitted in new chemicals notices and improv[ng] the Agency's processes to reduce unnecessary rework in the risk assessment.” Increasing initial PMN quality and reducing rework will help the Agency address ongoing challenges to completing PMN reviews within the statutory 90-day review period. While EPA is barred from requiring a minimum data set for PMN applications,