Explore the role of CRISPR gene editing in target validation

Target validation is a crucial step in pre-clinical drug discovery workflows that builds confidence on the identification of a genetic target as relevant to a disease. With recent advancements, CRISPR serves as a particularly powerful tool for this process, as it enables researchers to accurately modify genes and determine their function in a variety of experimental systems.

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Yu Holly Chen , Sergio Casas , Panos Zalmas , Rinki Ratnapriya , Krishanu Saha , Wellcome Sanger Institute , Institute For Rare Diseases Research , University Of Alabama At Birmingham , Validation Lab , University Of Wisconsin , Head Of The Open Targets Validation Lab , Baylor College Of Medicine , Editorial Article , Open Targets Validation Lab , Wellcome Sanger , Genome Editor , Thermo Fisher Scientific , Baylor College , Sergio Casas Tint , Drosophila Models , Human Disease Unit , Rare Diseases Research , Explore The Role Of Crispr Gene Editing In Target Validation Selectscience Zalmas , Rispr , Drug Development , Gene Editing , Workflow ,