Helium Leak Detection Webinars Announced For April 8 And May 13 April 8: Helium Leak Detection: History, Principle of Operation, and Methods for Pharmaceutical Packaging Helium mass spectrometry has a long history of implementation for high-sensitivity leak detection in a range of industries. Intended for individuals of all CCI experience levels, this first of two helium-related webinars provides participants with historical context on the use of helium leak detection, an understanding of its key operating principles, and how the technology is most commonly applied to assess pharmaceutical packaging. As with all CCI methods, helium leak detection has advantages and disadvantages that largely dictate the applicability of the technology in a specific use-case. Key considerations for applications of helium shall be discussed, including a brief comparison to other deterministic CCI methodologies listed in USP 1207 .