How and when to submit research applications to ARSAC Guide to submitting research applications to the Administration of Radioactive Substances Advisory Committee (ARSAC). From: Contents ARSAC) research approval for all your research projects where the protocol: requires the administration of radioactive substances specifies the frequency, activity or processing for an administration that would otherwise be considered standard care You do not need to obtain ARSAC research approval for research projects where: the protocol does not specify any administrations of radioactive substances the only administration of a radioactive substance mentioned in the protocol is an inclusion criterion that would be received by all participants as part of standard care, for example, a trial where all participants must have received a radioiodine therapy to be considered eligible