In late 2020, Keke Palmer made the decision to share a deeply intimate part of her health story: She’s one of the one in 10 women who lives with polycystic ovarian syndrome (PCOS) — the most common hormonal endocrine disorder in women. Characterized by small cysts growing on the ovaries and excess testosterone in the body, people dealing with PCOS are known to experience symptoms like hair loss, excess facial hair, cystic acne, weight gain, and fertility issues (due to the testosterone keeping ovaries from releasing eggs). In a video shared on Instagram, Palmer was totally frank about her PCOS and how long she’d dealt with its side effects — particularly her lifelong struggle with painful cystic acne — and her struggle to get an accurate diagnosis over the years.