Report: John Stamos Working On Stand-Up Comedy Act With Help From An Old Friend M John Stamos seeking a career change? About a year ago, one report said the Fuller House star was working on a career in stand-up comedy with the help of his co-star Bob Saget. According to Star, John Stamos has high hopes for his new career as a stand-up comic. A source says Stamos “has always wanted to develop a nightclub act where he can mix comedy with a little music.” Friend and Full Houseco-star Bob Saget has, a source says, “been giving him feedback on his jokes and advice about how to carry himself on stage.”