Surge expected. Mandatory evacuations in effect, and were tracking it all. Also this evening, President Bidens final address at the united nations. His warning to the world as Wars Rage in the Middle East and eastern europe. Israel and hezbollah exchanging new strikes as thousands flee Southern Lebanon after the deadliest day there in almost two decades. Nearly a year after the Hamas Terror Attack on israel, the families of american hostages speaking out. One freed hostage fearing for her husband still in captivity. I was in those same conditions, and i thought im going to die all the time. Do they feel forgotten as the War Shifts to lebanon. Nfl Legend Brett Favre revealing his battle with parkinsons while on the Hot Seat at a Capitol Hill hearing. Lawmakers demanding to know why are popular Weight Loss drugs so expensive when they cost less abroad. And the wnba playoffs Tipping Off as the popularity of womens hoops surges on courts across the country. Announcer this is Nbc Nightly News with lester holt. Good evening, everyone, and welcome. We may be looking at a major hurricane striking the u. S. Mainland within the next 48 hours. As we come on the air, heres what forecasters are watching. What is right now tropical Storm Helene is organizing and gaining strength, likely to reach Hurricane Status by tomorrow before making landfall in florida some time Thursday Evening potentially as a category 3 hurricane. Helene forecasted to bring Drenching Rains and Storm Surge as high as 15 feet. Hurricane and Storm Surge alerts are already posted along the entire West Coast of florida, and residents are being urged to finish their preparations. Well show you some of those preparations in a moment. But first, we turn to Bill Karins for the latest storm track. And bill, how does it all Time Out . Lester, 48 hours from now, we expect a major Hurricane Landfall with an impressive Storm Surge, dangerous winds, and of course all the rain thats going come with it. The storm is still organizing. Right now its just a tropical storm. By tomorrow morning, near cancun, possibly a category 1 hurricane. Then its over very warm water for about 36 hours. Thats when we could have rapid intensification. Thats when the Hurricane Center has it paralleling the West Coast of Florida On Thursday and making landfall about 9 00 p. M. Somewhere south of tallahassee, and then friday traveling up through georgia and raining itself out in the southern appalachians. As far as the storm goes, dont focus on the cones. This storm is huge. About 400 mile wide tropical stormforce winds. Well away from the center intense impact and Storm Surge up to 15 feet. All right, bill, thanks very much. Marissa parra is in tampa for us tonight. Marissa, a State Of Emergency is in effect there and in most of florida, in fact. Lester, thats right. That is why were seeing preparations days ahead of landfall. Right next to me, on the right is an aqua fence, and this is what is expected to protect Tampa General Hospital on the other side of the fence from the Tampa Bay just feet away from us. Now where we are in tampa, this someone of the counties, one of the at least 61 counties that has declared a State Of Emergency that is most of the state of florida. And as bill just pointed out, the massive size of the storm. Remember, its not just those in the direct path. The biggest threat is often going to be the flooding and the Storm Surge. This is why we are already seeing long lines at the Sandbag Distribution centers, at the Gas Station School closures across the state. The message here, lester, tonight is clear. Prepare now while you can. Marissa parra, thank you. Here in new york, President Biden took the world stage today, weighing in on the wars in the middle East And Ukraine in his final speech before the u. N. General assembly. Peter alexander now with his urgent message. Tonight, President Bidens farewell to the u. N. his fourth and final address. The choices we make today will determine our future for decades to come. Reporter with fears the violence between Israel And Hezbollah could grow, the president again today calling for a negotiated end to the conflict in the Middle East. Fullscale war is not in anyones interest, even if the situation is escalated, a diplomatic solution is still possible. Reporter but for months a Ceasefire And Hostage deal have remained elusive. The president also bluntly insisting that russian president vladimir Putins Invasion of ukraine has failed, touting the strength of alliances he helped expand. You cannot grow weary. We cannot look away. And we will not let up on our support for ukraine. Reporter three years after declaring america is back following former President Trumps time in office. Deliver for our own people. We must also engage deeply with the rest of the world. Reporter the question looming over this years u. N. Whether trump and his America First policies are coming back. Our test is to make sure that the forces holding us together are stronger than those that are pulling us apart. Reporter but tonight republicans argue the world has grown more dangerous since President Biden took office. What weve seen is chaos throughout the world is america and our allies safer today than it was four years ago . The answer is absolutely not. Reporter reflecting on his five decades in public life, including his abrupt decision to step aside under pressure from within his own party. This powerful message to democratic leaders and dictators alike. Let us never forget some things are more important than staying in power. Its your people that matter the most. And peter, weve just learned israels prime Minister Benjamin Netanyahu will speak on friday. Thats right, lester. President biden is not as of this moment expected to meet with him while he is here. Meanwhile we do know both the president and the Vice President will be meeting with Ukraines President Zelenskyy later this week. Zelenskyy will also meet with President Trump while here. Okay, peter, thank you. And in the Middle East, israel widened its deadly Air Assault on hezbollah targets in Southern Lebanon today, Forcing Tens Of Thousands to escape from the region. Matt bradley is in beirut now with late details. Reporter Israel Petroleum Milling lebanons hezbollah Militant Group for a second day, a day after inflicting the highest Death Toll in lebanon since the 2006 war. The twoday Death Toll more than 550 people according to the lebanese health ministry, and nearly 2,000 more injured. The enemy doesnt differentiate between civilians and militants, this man said. Were all civilians. The israeli military releasing this video of a strike in beirut it says killed a top hezbollah commander. Prime Minister Benjamin Netanyahu vowed today to keep it up, urging lebanese citizens to rid themselves of hezbollah. Well continue to pound hezbollah, he said. Anyone who has a missile in their Living Room and a rocket in their garage will not have a home. Hezbollah has been firing back, launching projectiles over the border towards israeli towns. The huge uptick in israeli strikes sparking a panicked exodus in lebanon south. Traffic backed up for hours for those fleeing, some with serious injuries. This hospital has already received dozens of injuries from the south. Some of them are being intubated in the icu, but theyre preparing to get even more. Doctors here say all of the injured they treated were civilians. We received usual war injuries, chest, broken leg, abdominal injuries. Reporter many who escape Death And Jury have found themselves homeless. Seeking refuge in makeshift shelters, Ilham Abdullah fled Southern Lebanon with her family and only the clothes on their backs. She said after they fled, half of her home was leveled by israeli strikes. Theres no house, she told me. And when i asked her when i asked her if she was afraid for the future, she said of course. And matt, you were in beirut tonight. Youve talked to people. What is the sense of their biggest concerns right now . Well, lester, following those huge aerial bombardments and those Walkietalkie And Pager explosions last week, the worry here is israel could be preparing for a Ground Invasion of the kind we saw back in 2006 that laid waste to Southern Lebanon. Lester . All right. Matt bradley tonight, thank you. The escalation of the mid East War threatens to overshadow the unresolved Hostage Crisis in gaza. Today i sat down with anguished american families still waiting to bring their Loved Ones home nearly a year after the October 7th hamas attacks. Its been nearly a year now since we first saw their faces, those kidnapped by hamas terrorists on October 7th, including the families of these americans who we spoke to today. Are you fearful that the Worlds Attention is shifting away from gaza and the hostages . Were here today again to appeal to the people of the world that are failing to see who are the innocents here. The innocents are our Loved Ones and the citizens of gaza and the region that just wants deescalation and just wants the war to end. And that should start with the release of the hostages. Reporter weve been speaking with these families since their nightmare began. But this is our first conversation with aviva siegel. She was a hostage herself, freed last year. But her husband keith is still being held. Keith and the hostages are thrown underneath the ground on a dirty mattress with no human rights. Theyre not allowed to talk. Theyre not allowed to move. Its dark there. Theyve got no oxygen. But for us worrying about them and me sick to my stomach worried about keeping oxygen. Because they are there and theyre just waiting. What will be the next thing the hamas terrorists will do to them. If theyre going rape them again, starve them again, hit them again. I was there in those same conditions, and i thought that im going to die all the time. Its hard to hear these stories. Yael, what is it like to hear these stories for you . Yaels 20yearold Son edan was also kidnapped. Very hard stories to hear. Like im worried sick for the wellbeing of edan. Every time im meeting aviva, im giving her the biggest hug i can. And i feel like im hugging edan, because to see her its like a miracle for me. She is like an angel. Mika is edans sister. It was so surreal like texting and talking to edan like two days before, and then hearing on October 7th that i was just not going to be talking to him. And now its been a year. So its been a year that my best, like that i was growing up with has just been, like gone from my life. Im sorry. No, its okay. Its very difficult. And aviva, at the same time, looking at you here, it is a sign of hope that it is possible. Its a sign of hope. But i wanted to look strong. Im broken up into pieces for all the families and the hostages that are there. Im going to scream as much as i can until they come back. How would you describe this past year . We simply just miss them so deeply, so deeply. My sister and her husbands bodies are being held as Bargaining Chips still in gaza. We cannot do anything besides trying to think how to get back itay home. And no joy in our life. The group has met frequently with biden administration officials. Is there a deal to be done between perhaps just the u. S. an independent deal . Is that doable . I believe that the administration needs to look at all of its basic assumptions, reevaluate them each day all over again, and see what is the best way to get its citizens out. The u. S. Has an obligation to get them out of harms way. Governments at this point in order to end the madness have to be willing to get out of their Comfort Zones to press hamas first and foremost. One year on, its almost too much to bear. Lester, while walking up here from the train this morning, a person saw my Shirt And Kind of threw haphazardly, do you really think there is anyone alive there . And i told him yes, i do. Its my son there. What do you mean . Yes, my son is there. Can you imagine what a nightmare it is to wake up every morning and not know if your child is alive, to know that in this horrible conditions for almost a year now, and that their lives is at stake every single day. Part of our emotional conversation earlier today here in new york. Well take a break. And in 60 seconds, the Justice Department accuses visa of illegally monopolizing Debit Card transactions, saying it has cost consumers and merchants billions in fees. Plus Hall Of Famer Brett Favre reveals his health battle. Stay with us. Might keep us stuck on the couch. No way. if you have postmenopausal osteoporosis and are at high risk for fracture, you can do more than just slow bone loss. You can build new bone in just 12 months with evenity. Evenity is proven to reduce Spine Fracture Risk by 73 . I heard her say the evenity shes taking builds new bone. Builds new bone evenity can increase risk of Heart Attack, stroke, or death from a cardiovascular problem. Do not take evenity if you have low Blood Calcium or are allergic to it. Serious allergic reactions and low Blood Calcium have occurred. Tell your doctor about Jaw Bone problems, as they have been reported with evenity. Or about pain in your hip, groin, or thigh, as unusual Thigh Bone fractures have occurred. Building new bone. We dig it. Want stronger bones . Ask your doctor about Building New Bone with evenity. After taking on google and ticketmaster, the Justice Department now has its sights on visa. The doj filing a major Antitrust Lawsuit over visas Debit Cards. Christine romans is here. Christine, how does the government say visa is hurting consumers . Because the Justice Department accuses Visa Of Killing Competition and running an illegal monopoly that raises prices for just about everything. According to the complaint, more than 60 of Debit Transactions in the u. S. Run on visas network, and that allows to it charge more than 7 Billion in fees, Transaction Fees each year. The Justice Department says visa does that by penalizing companies for not exclusively using its payment processing network. Retailers have complained for years of the high costs of Processing Debit and Credit Card payments. The government says those fees are passed to consumers. Now a Visa Spokesperson called the suit meritless, saying there is an ever expanding universe of companies offering new ways to pay for goods and services. They say Todays Lawsuit ignores the reality that visa is just one of many competitors in the Debit Space that is growing. But this is the latest move in a tough antitrust stance from the government, also targeting online ticketing and digital advertising, lester. All right, christine romans, thank you. On Capitol Hill, a major announcement from Legendary Nfl quarterback Brett Favre. The 54yearold Hall of famer telling lawmakers he has been diagnosed with parkinsons disease. It came during a hearing on the alleged Misu Funds in mississippi. Favre has been accused of accepting more than A Million dollars in fees from a Welfare Program for speeches he never gave. He denied wrongdoing, paid back the money, and has not been criminally charged, but was named in a civil lawsuit filed by the state. 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